Evidence map›Paper›PMID 28159755›Full record

ArticleGenetics2017

Role of Ectopic Gene Conversion in the Evolution of a

Erwin Lamping, Jing-Yi Zhu, Masakazu Niimi, Richard David Cannon

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Genomic Insights ofOpen forum infectious diseases · 2026
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  4. Genomic analyses reveal high diversity and rapid evolution ofAntimicrobial agents and chemotherapy · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. PDR TransporterFrontiers in microbiology · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Erwin LampingSir John Walsh Research Institute, University of Otago, Dunedin 9054, New Zealand erwin.lamping@otago.ac.nz.ORCID 0000-0002-4942-4782
Jing-Yi ZhuSir John Walsh Research Institute, University of Otago, Dunedin 9054, New Zealand.
Masakazu NiimiSir John Walsh Research Institute, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0002-1333-1939
Richard David CannonSir John Walsh Research Institute, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0002-5398-2066
University of Otago · NZ

Funding

Fungal transporters: from resistance to new antifungalsR01DE016885 · NIDCR · UNIVERSITY OF OTAGO · PI CANNON, RICHARD D · 2005 to 2008
$927k
NIDCR NIH HHS R01 DE016885
6 · The paper itself

Abstract

Gene duplications enable the evolution of novel gene function, but strong positive selection is required to preserve advantageous mutations in a population. This is because frequent ectopic gene conversions (EGCs) between highly similar, tandem-duplicated, sequences, can rapidly remove fate-determining mutations by replacing them with the neighboring parent gene sequences. Unfortunately, the high sequence similarities between tandem-duplicated genes severely hamper empirical studies of this important evolutionary process, because deciphering their correct sequences is challenging. In this study, we employed the eukaryotic model organism

Indexed as

Evolution, MolecularGene ConversionGenetic PleiotropyATP-Binding Cassette, Sub-Family C ProteinsCandidaDNA Copy Number VariationsDrug Resistance, FungalFungal ProteinsATP-Binding Cassette, Sub-Family C ProteinsFungal ProteinsCandida kruseicopy number variationevolution of multi-gene familiesgene duplication and gene conversionPDR transporters

Identifiers

PMID28159755
PMCPMC5378117
OpenAlexW2584958683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.