Evidence map›Paper›PMID 28159652›Full record

ArticleHearing research2017

Auditory brainstem response latency in forward masking, a marker of sensory deficits in listeners with normal hearing thresholds.

Golbarg Mehraei, Andreu Paredes Gallardo, Barbara G Shinn-Cunningham, Torsten Dau

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hearing research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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  7. Auditory Spatial Perception as a Function of Recreational Noise Exposure in Gen-Z Adults with Normal Hearing.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  8. Review
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  13. Auditory and Visual System White Matter Is Differentially Impacted by Normative Aging in Macaques.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Golbarg MehraeiProgram in Speech and Hearing Bioscience and Technology, Harvard University-Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Center for Computational Neuroscience and Neural Technology, Boston University, Boston, MA, 02215, USA; Hearing Systems Group, Technical University of Denmark, Ørsteds Plads Building 352, 2800, Kongens Lyngby, Denmark. Electronic address: golmeh@elektro.dtu.dk.
Andreu Paredes GallardoHearing Systems Group, Technical University of Denmark, Ørsteds Plads Building 352, 2800, Kongens Lyngby, Denmark.
Barbara G Shinn-CunninghamProgram in Speech and Hearing Bioscience and Technology, Harvard University-Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Center for Computational Neuroscience and Neural Technology, Boston University, Boston, MA, 02215, USA; Department of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.
Torsten DauHearing Systems Group, Technical University of Denmark, Ørsteds Plads Building 352, 2800, Kongens Lyngby, Denmark.
Boston University · USØrsted (Denmark) · DK

Funding

Individual differences in supra-threshold sound encodingR01DC013825 · NIDCD · CARNEGIE-MELLON UNIVERSITY · PI SHINN-CUNNINGHAM, BARBARA · 2015 to 2019
$1.7M
NIDCD NIH HHS R01 DC013825
6 · The paper itself

Abstract

In rodent models, acoustic exposure too modest to elevate hearing thresholds can nonetheless cause auditory nerve fiber deafferentation, interfering with the coding of supra-threshold sound. Low-spontaneous rate nerve fibers, important for encoding acoustic information at supra-threshold levels and in noise, are more susceptible to degeneration than high-spontaneous rate fibers. The change in auditory brainstem response (ABR) wave-V latency with noise level has been shown to be associated with auditory nerve deafferentation. Here, we measured ABR in a forward masking paradigm and evaluated wave-V latency changes with increasing masker-to-probe intervals. In the same listeners, behavioral forward masking detection thresholds were measured. We hypothesized that 1) auditory nerve fiber deafferentation increases forward masking thresholds and increases wave-V latency and 2) a preferential loss of low-spontaneous rate fibers results in a faster recovery of wave-V latency as the slow contribution of these fibers is reduced. Results showed that in young audiometrically normal listeners, a larger change in wave-V latency with increasing masker-to-probe interval was related to a greater effect of a preceding masker behaviorally. Further, the amount of wave-V latency change with masker-to-probe interval was positively correlated with the rate of change in forward masking detection thresholds. Although we cannot rule out central contributions, these findings are consistent with the hypothesis that auditory nerve fiber deafferentation occurs in humans and may predict how well individuals can hear in noisy environments.

Indexed as

Acoustic StimulationAdultAfferent PathwaysAnimalsAuditory PerceptionAuditory ThresholdCochleaCochlear NerveEvoked Potentials, Auditory, Brain StemFemaleHumansMaleModels, NeurologicalNoisePerceptual MaskingReaction TimeAuditory brainstem responseCochlear synaptopathyForward maskingHidden hearing loss

Identifiers

PMID28159652
PMCPMC5402043
OpenAlexW2585502825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.