Evidence map›Paper›PMID 28159600›Full record

ReviewThe American journal of medicine2017

Oral Anticoagulant Use After Bariatric Surgery: A Literature Review and Clinical Guidance.

Karlyn A Martin, Craig R Lee, Timothy M Farrell, Stephan Moll

Open access · bronzeAbstract readReview
In one paragraph

Review in The American journal of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
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  11. Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
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  15. Article
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  19. DOACs: role of anti-Xa and drug level monitoring.Hematology. American Society of Hematology. Education Program · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Karlyn A MartinDivision of Hematology/Oncology, University of North Carolina at Chapel Hill. Electronic address: Karlyn.martin@northwestern.edu.
Craig R LeeEshelman School of Pharmacy, University of North Carolina at Chapel Hill.
Timothy M FarrellDivision of Gastrointestinal Surgery, University of North Carolina at Chapel Hill.
Stephan MollDivision of Hematology/Oncology, University of North Carolina at Chapel Hill.
University of North Carolina at Chapel Hill · US

Funding

Research Training in Hematology at UNC Chapel HillT32HL007149 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Nigel S. Key · 1985 to 2026
$8.6M
NHLBI NIH HHS T32 HL007149
6 · The paper itself

Abstract

Bariatric surgery may alter the absorption, distribution, metabolism, or elimination (disposition) of orally administered drugs via changes to the gastrointestinal tract anatomy, body weight, and adipose tissue composition. As some patients who have undergone bariatric surgery will need therapeutic anticoagulation for various indications, appropriate knowledge is needed regarding anticoagulant drug disposition and resulting efficacy and safety in this population. We review general considerations about oral drug disposition in patients after bariatric surgery, as well as existing literature on oral anticoagulation after bariatric surgery. Overall, available evidence on therapeutic anticoagulation is very limited, and individual drug studies are necessary to learn how to safely and effectively use the direct oral anticoagulants. Given the sparsity of currently available data, it appears most prudent to use warfarin with international normalized ratio monitoring, and not direct oral anticoagulants, when full-dose anticoagulation is needed after bariatric surgery.

Indexed as

Bariatric SurgeryAbsorption, PhysiologicalAdministration, OralAnticoagulantsBiological AvailabilityDrug MonitoringEnergy IntakeHumansVitamin KWarfarinWeight LossAnticoagulantsVitamin KWarfarinAbsorptionAnticoagulationApixabanBariatric surgeryBiliopancreatic diversionBleedingDabigatranEdoxabanEfficacyGastrectomyGastric bandingObesityPharmacokineticsRivaroxabanRoux-en-YSafetyThrombosisWarfarin

Identifiers

PMID28159600
PMCPMC5401640
OpenAlexW2583390449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.