Trial reportCritical care (London, England)2017
The effects of low tidal ventilation on lung strain correlate with respiratory system compliance.
Trial report in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
the Influence of Different Tidal Volume to Lung Strain of ARDS Patients
A Randomized Controlled Trial to Assess the Feasiblity of a Driving Pressure Limited Ventilation vs.Standard Strategy During Video-assisted Thoracoscopic Lobectomy
Who cites it
18 citing papers in PubMed.
- The effects of low tidal ventilation on lung strain correlate with respiratory system compliance.Critical care (London, England) · 2017Trial
- Acute Respiratory Distress Syndrome: Pathophysiological Insights, Subphenotypes, and Clinical Implications-A Comprehensive Review.Journal of clinical medicine · 2025Review
- Driving pressure in acute respiratory distress syndrome for developing a protective lung strategy: A systematic review.World journal of critical care medicine · 2025Article
- Effects of secular changes in tidal volume and respiratory rate on the mechanical power of ventilation: a retrospective single-center study of invasively ventilated patients.Critical care science · 2025Article
- Associated effects of lipopolysaccharide, oleic acid, and lung injury ventilator-induced in developing a model of moderate acute respiratory distress syndrome in New Zealand white rabbits.Frontiers in veterinary science · 2025Article
- Feasibility of Setting the Tidal Volume Based on End-Expiratory Lung Volume: A Pilot Clinical Study.Critical care explorations · 2024Article
- Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway.Frontiers in pharmacology · 2024Article
- Reactive Oxygen Species and Strategies for Antioxidant Intervention in Acute Respiratory Distress Syndrome.Antioxidants (Basel, Switzerland) · 2023Review
- Mechanical Power Correlates With Stress, Strain, and Atelectrauma Only When Normalized to Aerated Lung Size in Patients With Acute Respiratory Distress Syndrome.Critical care explorations · 2023Article
- [Less is not always more].Medicina intensiva · 2022Article
- Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip.Nature communications · 2022Article
- Myths and Misconceptions of Airway Pressure Release Ventilation: Getting Past the Noise and on to the Signal.Frontiers in physiology · 2022Review
- Tidal Volume Lowering by Instrumental Dead Space Reduction in Brain-Injured ARDS Patients: Effects on Respiratory Mechanics, Gas Exchange, and Cerebral Hemodynamics.Neurocritical care · 2021Article
- Article
- What links ventilator driving pressure with survival in the acute respiratory distress syndrome? A computational study.Respiratory research · 2019Article
- Deferoxamine preconditioning ameliorates mechanical ventilation-induced lung injury in rat model via ROS in alveolar macrophages: a randomized controlled study.BMC anesthesiology · 2018Article
- Acute Respiratory Distress Syndrome: Challenge for Diagnosis and Therapy.Chinese medical journal · 2018Review
- Driving airway and transpulmonary pressure are correlated to VILI determinants during controlled ventilation.Intensive care medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effect of alterations in tidal volume on mortality of acute respiratory distress syndrome (ARDS) is determined by respiratory system compliance. We aimed to investigate the effects of different tidal volumes on lung strain in ARDS patients who had various levels of respiratory system compliance.
methodsNineteen patients were divided into high (C
resultsThe mean baseline EELV, strain and respiratory system compliance values were 1873 ml, 0.31 and 0.65 ml/(cmH
conclusionsRespiratory system compliance affected the relationships between tidal volume and driving pressure and lung strain in ARDS patients. These results showed that increasing tidal volume induced lung injury more easily in patients with low respiratory system compliance.
trial registrationClinicaltrials.gov identifier NCT01864668 , Registered 21 May 2013.
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