Evidence map›Paper›PMID 28159004›Full record

ReviewGenome biology2017

Software tools for visualizing Hi-C data.

Galip Gürkan Yardımcı, William Stafford Noble

Abstract readReview
In one paragraph

Review in Genome biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Mapping the 3D genome architecture.Computational and structural biotechnology journal · 2025
    Review
  4. ppHiC: Interactive exploration of Hi-C results on the ProteinPaint web portal.Computational and structural biotechnology journal · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  11. Review
  12. Article
  13. Methods for the Differential Analysis of Hi-C Data.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Galip Gürkan YardımcıDepartment of Genome Sciences, University of Washington, 3720 15th Ave NE, Seattle, 98105, WA, USA.ORCID 0000-0001-7283-4715
William Stafford NobleDepartment of Genome Sciences, Department of Computer Science and Engineering, University of Washington, 3720 15th Ave NE, Seattle, 98105, WA, USA. william-noble@uw.edu.

Funding

University of Washington Center for Nuclear Organization and FunctionU54DK107979 · NIDDK · UNIVERSITY OF WASHINGTON · PI NOBLE, WILLIAM STAFFORD, SHENDURE, JAY ASHOK · 2015 to 2019
$11.8M
EDAC: ENCODE Data Analysis CenterU41HG007000 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI WENG, ZHIPING · 2012 to 2016
$9.8M
NHGRI NIH HHS U41 HG007000NIDDK NIH HHS U54 DK107979
6 · The paper itself

Abstract

High-throughput assays for measuring the three-dimensional (3D) configuration of DNA have provided unprecedented insights into the relationship between DNA 3D configuration and function. Data interpretation from assays such as ChIA-PET and Hi-C is challenging because the data is large and cannot be easily rendered using standard genome browsers. An effective Hi-C visualization tool must provide several visualization modes and be capable of viewing the data in conjunction with existing, complementary data. We review five software tools that do not require programming expertise. We summarize their complementary functionalities, and highlight which tool is best equipped for specific tasks.

Indexed as

GenomeModels, MolecularNucleic Acid ConformationSoftwareAnimalsDatasets as TopicDNAGenomicsHumansImaging, Three-DimensionalWeb BrowserDNA

Identifiers

PMID28159004
PMCPMC5290626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.