ArticleSocial cognitive and affective neuroscience2017
Trait anxiety mediates the link between inferior frontal cortex volume and negative affective bias in healthy adults.
Article in Social cognitive and affective neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide.Molecular psychiatry · 2026Article
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- Neuroanatomical prediction of individual anxiety problems level using machine learning models: A population-based cohort study of young adults.Neurobiology of stress · 2025Article
- Graph analysis of guilt processing network highlights links with subclinical anxiety and self-blame.Social cognitive and affective neuroscience · 2024Article
- Interplay among Anxiety, Digital Environmental Exposure, and Cognitive Control: Implications of Natural Settings.Behavioral sciences (Basel, Switzerland) · 2024Article
- Effects of emotional congruency and task complexity on decision-making.Cognitive processing · 2023Article
- Anxious Brains: A Combined Data Fusion Machine Learning Approach to Predict Trait Anxiety from Morphometric Features.Sensors (Basel, Switzerland) · 2023Article
- Distinct Effects of Anxiety and Depression on Updating Emotional Information in Working Memory.International journal of environmental research and public health · 2022Article
- State and Trait Anxiety Share Common Network Topological Mechanisms of Human Brain.Frontiers in neuroinformatics · 2022Article
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- Religiosity and Resilience: Cognitive Reappraisal and Coping Self-Efficacy Mediate the Link between Religious Coping and Well-Being.Journal of religion and health · 2021Article
- Cultivating Affective Resilience: Proof-of-Principle Evidence of Translational Benefits From a Novel Cognitive-Emotional Training Intervention.Frontiers in psychology · 2021Article
- The electrophysiology correlation of the cognitive bias in anxiety under uncertainty.Scientific reports · 2020Observational
- Trait and state anxiety are mapped differently in the human brain.Scientific reports · 2020Article
- Article
- Neurobehavioral Mechanisms of Resilience Against Emotional Distress: An Integrative Brain-Personality-Symptom Approach Using Structural Equation Modeling.Personality neuroscience · 2018Article
- Common and disorder-specific cortical thickness alterations in internalizing, externalizing and thought disorders during early adolescence: an Adolescent Brain and Cognitive Development study.Journal of psychiatry & neuroscience : JPNArticle
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2 authors.
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Abstract
Anxious individuals tend to show a negative affective bias in attention that likely reflects reduced executive control, a cognitive function associated with the inferior frontal cortex (IFC), particularly its posterior segment, pars opercularis. Here, we investigated the relations among gray matter volume in the pars opercularis of IFC, trait anxiety, and negative biases in attention, in healthy participants. Sixty-two adults underwent structural magnetic resonance imaging scanning, completed a trait anxiety measure, and performed an Affective Go/No-Go (AGN) task. IFC volumes were extracted using Freesurfer, and negative bias scores were calculated from AGN performance. Trait anxiety correlated negatively with left IFC volume, and positively with the negative bias in reaction time. Furthermore, trait anxiety mediated the negative relation between the IFC volume and the negative bias measure. Overall, the present findings extend previous understanding of the IFC involvement in anxiety at the structural level, and may inform the development of intervention programs targeting anxiety.
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