Evidence map›Paper›PMID 28157700›Full record

ArticleOncotarget2017

Impact of exudative diathesis induced by selenium deficiency on LncRNAs and their roles in the oxidative reduction process in broiler chick veins.

Changyu Cao, Ruifeng Fan, Jinxin Zhao, Xia Zhao, Jie Yang, Ziwei Zhang, Shiwen Xu

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Antagonistic Effects Of Baicalin OnInfection and drug resistance · 2019
    Article
  7. Article
  8. Selenium-Related Transcriptional Regulation of Gene Expression.International journal of molecular sciences · 2018
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Changyu CaoDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Ruifeng FanDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Jinxin ZhaoDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Xia ZhaoDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Jie YangDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Ziwei ZhangDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Shiwen XuDepartment of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, P. R. China.
Northeast Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium deficiency may induce exudative diathesis (ED) in broiler chick, and this damage is closely related to oxidative damage. Long noncoding RNA (LncRNA) can regulate the redox state in vivo. The aim of the present study was to clarify the LncRNA expression profile in broiler veins and filter and verify the LncRNAs related to oxidative damage of ED. This study established an ED model induced by selenium deficiency and presented the expression and characterization of LncRNAs in normal and ED samples. A total of 15412 LncRNAs (including 8052 novel LncRNAs) were generated in six cDNA libraries using the Illumina Hi-Seq 4000 platform. 635 distinct changes in LncRNAs (up-regulated fold change > 1.5, down-regulated fold change < 0.67 and differentially expressed LncRNAs) were filtered. Gene ontology enrichment on LncRNAs target genes showed that the oxidative reduction process was important. This study also defined and verified 19 target mRNAs of 23 LncRNAs related to the oxidative reduction process. The in vivo and vitro experiments also demonstrated these 23 LncRNAs can participate in the oxidative reduction process. This study presents LncRNAs expression profile in broiler chick veins for the first time and confirmed 23 LncRNAs involving in the vein oxidative damage in ED.

Indexed as

Oxidation-ReductionRNA, Long NoncodingAnimalsChickensDisease Models, AnimalEndothelial CellsMaleReal-Time Polymerase Chain ReactionSeleniumVeinsRNA, Long NoncodingSeleniumbroiler chick veinexudative diathesislong noncoding RNA-seqoxidative reduction processselenium deficiency

Identifiers

PMID28157700
PMCPMC5400537
OpenAlexW2585411197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.