ArticleScientific reports2017
Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Experimental Acute Exposure to Thirdhand Smoke and Changes in the Human Nasal Epithelial Transcriptome: A Randomized Clinical Trial.JAMA network open · 2019Trial
- Parental Smoking and E-cigarette Use in Homes and Cars.Pediatrics · 2019Trial
- A Critical Perspective on the Role of Thirdhand Smoke in Tumorigenesis: Initiator or Promoter.Environment & health (Washington, D.C.) · 2026Review
- Low dose thirdhand smoke exposure enhances platelet functional responses in mice.Experimental biology and medicine (Maywood, N.J.) · 2026Article
- Memory under siege: the cognitive costs of smoking and vaping.Brain, behavior, & immunity - health · 2025Review
- Beliefs about third-hand smoke and health perceptions of the preschool paediatric patients' parents.Central European journal of public health · 2025Article
- Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants.Tobacco control · 2024Article
- Thirdhand tobacco smoke exposure increases the genetic background-dependent risk of pan-tumor development in Collaborative Cross mice.Environment international · 2023Article
- The association between neurodevelopmental and behavioral problems and tobacco smoke exposure among 3-17 years old children.Frontiers in public health · 2022Article
- Genetic background influences the effect of thirdhand smoke exposure on anxiety and memory in Collaborative Cross mice.Scientific reports · 2021Article
- Thirdhand cigarette smoke leads to age-dependent and persistent alterations in the cecal microbiome of mice.MicrobiologyOpen · 2021Article
- In utero and early-life exposure to thirdhand smoke causes profound changes to the immune system.Clinical science (London, England : 1979) · 2021Article
- Adhesion and Removal of Thirdhand Smoke from Indoor Fabrics: A Method for Rapid Assessment and Identification of Chemical Repositories.International journal of environmental research and public health · 2021Article
- Beliefs of parents in Kuwait about thirdhand smoke and its relation to home smoking rules: A cross-sectional study.Tobacco induced diseases · 2021Article
- Thirdhand smoke exposure causes replication stress and impaired transcription in human lung cells.Environmental and molecular mutagenesis · 2020Article
- Thirdhand smoke: Genotoxicity and carcinogenic potential.Chronic diseases and translational medicine · 2020Article
- Human transport of thirdhand tobacco smoke: A prominent source of hazardous air pollutants into indoor nonsmoking environments.Science advances · 2020Article
- Thirdhand smoke uptake to aerosol particles in the indoor environment.Science advances · 2018Article
- Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice.Clinical science (London, England : 1979) · 2018Article
- Guidance for the Clinical Management of Thirdhand Smoke Exposure in the Child Health Care Setting.Journal of clinical outcomes management : JCOM · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Thirdhand smoke (THS) is the fraction of cigarette smoke that persists in indoor environments after smoking. We investigated the effects of neonatal and adult THS exposure on bodyweight and blood cell populations in C57BL/6 J mice. At the end of neonatal exposure, THS-treated male and female mice had significantly lower bodyweight than their respective control mice. However, five weeks after neonatal exposure ended, THS-treated mice weighed the same as controls. In contrast, adult THS exposure did not change bodyweight of mice. On the other hand, both neonatal and adult THS exposure had profound effects on the hematopoietic system. Fourteen weeks after neonatal THS exposure ended, eosinophil number and platelet volume were significantly higher, while hematocrit, mean cell volume, and platelet counts were significantly lower compared to control. Similarly, adult THS exposure also decreased platelet counts and increased neutrophil counts. Moreover, both neonatal and adult THS exposure caused a significant increase in percentage of B-cells and significantly decreased percentage of myeloid cells. Our results demonstrate that neonatal THS exposure decreases bodyweight and that THS exposure induces persistent changes in the hematopoietic system independent of age at exposure. These results also suggest that THS exposure may have adverse effects on human health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.