Evidence map›Paper›PMID 28157162›Full record

ReviewNutrients2017

Evidence of Some Natural Products with  Antigenotoxic Effects. Part 1: Fruits and  Polysaccharides.

Jeannett Alejandra Izquierdo-Vega, José Antonio Morales-González, Manuel SánchezGutiérrez, Gabriel Betanzos-Cabrera, Sara M Sosa-Delgado, María Teresa Sumaya-Martínez, Ángel Morales-González, Rogelio Paniagua-Pérez, Eduardo Madrigal-Bujaidar, Eduardo Madrigal-Santillán

Abstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Genoprotective Properties ofInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Review
  4. Exploring the Antioxidant and Genoprotective Potential ofAnimals : an open access journal from MDPI · 2023
    Article
  5. Article
  6. Article
  7. The Therapeutic Efficacy ofPlants (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeannett Alejandra Izquierdo-VegaInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hidalgo, México.  jizquierdovega@gmail.com.
José Antonio Morales-GonzálezEscuela Superior de Medicina, Instituto Politécnico Nacional, Unidad Casco de Santo Tomas, Plan de San Luis y Díaz Mirón s/n, México D.F. 11340, México.  jmorales101@yahoo.com.mx.
Manuel SánchezGutiérrezInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hidalgo, México. spmtz68@yahoo.com.mx.
Gabriel Betanzos-CabreraInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hidalgo, México.  gbetanzo@uaeh.edu.mx.
Sara M Sosa-DelgadoEscuela Superior de Medicina, Instituto Politécnico Nacional, Unidad Casco de Santo Tomas, Plan de San Luis y Díaz Mirón s/n, México D.F. 11340, México. sara.odet26@gmail.com.
María Teresa Sumaya-MartínezSecretaría de Investigación y Estudios de Posgrado, Universidad Autónoma de Nayarit, Ciudad de la Cultura Amado Nervo. Boulevard Tepic-Xalisco s/n, Tepic 28000, Nayarit, México. teresumaya@hotmail.com.
Ángel Morales-GonzálezEscuela Superior de Cómputo, Instituto Politécnico Nacional, Unidad A. López Mateos, Av. Juan de Dios Bátiz. Col., Lindavista, México D.F. 07738, Mexico. anmorales@ipn.mx.
Rogelio Paniagua-PérezLaboratorio de Bioquímica Muscular, Instituto Nacional de Rehabilitación, Av. México-Xochimilco. Col., Arenal de Guadalupe, México D.F. 14389, México. rogelpp@yahoo.com.
Eduardo Madrigal-BujaidarEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, Unidad A. López-Mateos, Av. Wilfrido Massieu s/n, Lindavista, México D.F. 07738, México. eduardo.madrigal@lycos.com.
Eduardo Madrigal-SantillánEscuela Superior de Medicina, Instituto Politécnico Nacional, Unidad Casco de Santo Tomas, Plan de San Luis y Díaz Mirón s/n, México D.F. 11340, México. eomsmx@yahoo.com.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading causes of deaths worldwide. The agents capable of causing damage to genetic material are known  as genotoxins and, according to their mode of action, are classified into mutagens, carcinogens or teratogens. Genotoxins are  involved in the pathogenesis of several chronic degenerative diseases including hepatic, neurodegenerative and cardiovascular  disorders, diabetes, arthritis, cancer, chronic inflammation and ageing. In recent decades, researchers have found novel bioactive  phytocompounds able to counteract the effects of physical and chemical mutagens. Several  studies  have  shown potential antigenotoxicity in a variety of fruits. In this review (Part 1), we present an overview of research conducted on some fruits (grapefruit, cranberries, pomegranate, guava, pineapple, and mango) which are frequentl consumed by humans, as well as  the  analysis of some phytochemicals extracted from fruits and yeasts which have demonstrated antigenotoxic capacity in various  tests, including the Ames assay, sister chromatid exchange, chromosomal aberrations, micronucleus and comet assay.

Indexed as

Antimutagenic AgentsFruitHumansMutagenesisMutagensPhytochemicalsPlant ExtractsPolysaccharidesAntimutagenic AgentsMutagensPhytochemicalsPlant ExtractsPolysaccharidesantigenotoxiccancerchromosomal aberrationscomet assayfruitsmicronucleuspolysaccharides

Identifiers

PMID28157162
PMCPMC5331533

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.