Evidence map›Paper›PMID 28156178›Full record

ReviewDrug delivery2017

Polyphenols delivery by polymeric materials: challenges in cancer treatment.

Orazio Vittorio, Manuela Curcio, Monica Cojoc, Gerardo F Goya, Silke Hampel, Francesca Iemma, Anna Dubrovska, Giuseppe Cirillo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Drug delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Nanoparticle-Based Combination Therapy for Ovarian Cancer.International journal of nanomedicine · 2023
    Review
  5. Article
  6. Chitosan-Polyphenol Conjugates for Human Health.Life (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Review
  9. Recent Advances in Phenolic Metabolites and Skin Cancer.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Delivery of natural phenolic compounds for the potential treatment of lung cancer.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2019
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Orazio Vittorioa UNSW Australia, Children's Cancer Institute, Lowy Cancer Research Center and ARC Center of Excellence in Convergent Bio-Nano Science and Technology, Australian Center for NanoMedicine , Sydney , NSW , Australia.
Manuela Curciob Department of Pharmacy Health and Nutritional Science , University of Calabria, Arcavacata di Rende , Italy.
Monica Cojocc OncoRay-National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf , Dresden , Germany.
Gerardo F Goyad Institute of Nanoscience of Aragon (INA) and Department of Condensed Matter Physics, University of Zaragoza , Zaragoza , Spain.
Silke Hampele Leibniz Institute of Solid State and Material Research Dresden , Dresden , Germany , and.
Francesca Iemmab Department of Pharmacy Health and Nutritional Science , University of Calabria, Arcavacata di Rende , Italy.
Anna Dubrovskac OncoRay-National Center for Radiation Research in Oncology, Medical Faculty and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf , Dresden , Germany.
Giuseppe Cirillob Department of Pharmacy Health and Nutritional Science , University of Calabria, Arcavacata di Rende , Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanotechnology can offer different solutions for enhancing the therapeutic efficiency of polyphenols, a class of natural products widely explored for a potential applicability for the treatment of different diseases including cancer. While possessing interesting anticancer properties, polyphenols suffer from low stability and unfavorable pharmacokinetics, and thus suitable carriers are required when planning a therapeutic protocol. In the present review, an overview of the different strategies based on polymeric materials is presented, with the aim to highlight the strengths and the weaknesses of each approach and offer a platform of ideas for researchers working in the field.

Indexed as

AnimalsDrug CarriersHumansNanoparticlesNanotechnologyNeoplasmsPolymersPolyphenolsDrug CarriersPolymersPolyphenolscancer therapyNanocarrierpolymeric materialspolyphenols

Identifiers

PMID28156178
PMCPMC8241076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.