Evidence map›Paper›PMID 28155878›Full record

ArticleScientific reports2017

Immune Signature of Enhanced Functional Avidity CD8

Zhidong Hu, Lingyan Zhu, Jing Wang, Yanmin Wan, Songhua Yuan, Jian Chen, Xiangqing Ding, Chenli Qiu, Xiaoyan Zhang, Chao Qiu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. CD3 downregulation identifies high-avidity human CD8 T cells.Clinical and experimental immunology · 2024
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zhidong HuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Lingyan ZhuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jing WangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yanmin WanShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Songhua YuanShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jian ChenShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Xiangqing DingShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Chenli QiuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Xiaoyan ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Chao QiuInstitutes of Biomedical Sciences, Fudan University, Shanghai, China.
Jianqing XuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Shanghai Public Health Clinical Center · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Functional avidity of T cells is a critical determinant for clearing viral infection and eliminating tumor. Understanding how functional avidity is maintained in T cells is imperative for immunotherapy. However, studies systematically characterize T cell with high functional avidity induced in vivo are still lacking. Previously, we and others found vaccinia vectored vaccine (VACV) induced antigen-specific CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCytokinesCytotoxicity, ImmunologicDisease Models, AnimalEpitopes, T-LymphocyteGene Expression ProfilingGenetic VectorsImmunizationImmunologic MemoryMiceModels, BiologicalMyeloid Differentiation Factor 88Signal TransductionT-Cell Antigen Receptor SpecificityTranscriptomeCytokinesEpitopes, T-LymphocyteMyeloid Differentiation Factor 88Vaccines, DNAViral Vaccines

Identifiers

PMID28155878
PMCPMC5290741
OpenAlexW2584682977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.