Evidence map›Paper›PMID 28155566›Full record

ArticleDrug delivery2017

In vivo synergistic anti-tumor effect of paclitaxel nanoparticles combined with radiotherapy on human cervical carcinoma.

YanXin Yu, Shan Xu, Hong You, YinJie Zhang, Bo Yang, XiaoYang Sun, LingLin Yang, Yue Chen, ShaoZhi Fu, JingBo Wu

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Histochemistry for Molecular Imaging in Nanomedicine.International journal of molecular sciences · 2024
    Review
  2. Review
  3. Review
  4. A Robust Oxygen Microbubble Radiosensitizer for Iodine-125 Brachytherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  5. Article
  6. Article
  7. ESR Method in Monitoring of Nanoparticle Endocytosis in Cancer Cells.International journal of molecular sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

YanXin Yua Department of Oncology and.
Shan Xua Department of Oncology and.
Hong Youa Department of Oncology and.
YinJie Zhanga Department of Oncology and.
Bo Yanga Department of Oncology and.
XiaoYang Suna Department of Oncology and.
LingLin Yanga Department of Oncology and.
Yue Chenb Department of Nuclear Medicine , the Affiliated Hospital of Southwest Medical University , Luzhou , China.
ShaoZhi Fua Department of Oncology and.
JingBo Wua Department of Oncology and.
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, our purpose was to explore the synergistic anti-tumor effect and mechanism of paclitaxel nanoparticles (PTX-NPs) combined with radiotherapy (RT) on human cervical carcinoma (HeLa). PTX-NPs were prepared by a solid dispersion method using methoxy poly(ethylene glycol)-poly(ɛ-caprolactone) (MPEG-PCL), which combined with RT exerted a potent and high efficient effect against cervical cancer. In vivo antitumor activity of PTX-NPs combined with RT, was estimated using nude mice carrying Hela cell xenograft tumor. The results were evaluated using microfluorine-18-deoxyglucose PET/computed tomography (

Indexed as

ChemoradiotherapyDrug CarriersNanoparticlesAngiogenesis InhibitorsAnimalsAntineoplastic Agents, PhytogenicCell ProliferationDrug CompoundingFemaleFluorodeoxyglucose F18HeLa CellsHumansImmunohistochemistryKi-67 AntigenMice, Inbred BALB CMice, NudeAngiogenesis InhibitorsAntineoplastic Agents, PhytogenicDrug CarriersFluorodeoxyglucose F18Ki-67 Antigenmethoxy poly(ethylene glycol-co-epsilon-caprolactone)PaclitaxelPlatelet Endothelial Cell Adhesion Molecule-1PolyestersPolyethylene GlycolsRadiopharmaceuticalsVascular Endothelial Growth Factor AVEGFA protein, humancervical cancernanoparticlePaclitaxelradiotherapysynergistic effect

Identifiers

PMID28155566
PMCPMC8241140
OpenAlexW2583889565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.