Evidence map›Paper›PMID 28155337›Full record

ArticleDrug delivery2017

Hyaluronic acid-modified didecyldimethylammonium bromide/ d-a-tocopheryl polyethylene glycol succinate mixed micelles for delivery of baohuoside I against non-small cell lung cancer: in vitro and in vivo evaluation.

Hongmei Yan, Jie Song, Xiaobin Jia, Zhenhai Zhang

Abstract readComparative Study
In one paragraph

Article in Drug delivery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. ω-Hydroxy isoprenoid bisphosphonates as linkable GGDPS inhibitors.Bioorganic & medicinal chemistry letters · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongmei Yana College of Pharmacy, Nanjing University of Chinese Medicine , Nanjing , PR China and.
Jie Songa College of Pharmacy, Nanjing University of Chinese Medicine , Nanjing , PR China and.
Xiaobin Jiaa College of Pharmacy, Nanjing University of Chinese Medicine , Nanjing , PR China and.
Zhenhai Zhangb Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Third School of Clinical Medical of Nanjing University of Chinese Medicine , Nanjing , PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baohuoside I is an effective but a poorly soluble antitumor drug. In this study, we prepared baohuoside I-loaded mixed micelles with didecyldimethylammonium bromide (DDAB) and d-a-tocopheryl polyethylene glycol succinate (TPGS) (DTBM) and active targeting mixed micelles (HDTBM) with hyaluronic acid (HA) as the targeting ligand on the surface of the mixed micelles. We performed a systematic comparative evaluation of the antiproliferative effect, cellular uptake, antitumor efficacy, and in vivo tumor targeting of these micelles using A549 cells. HDTBM showed improved cellular uptake and had a greater hypersensitizing effect on A549 cell lines than baohuoside I; half-maximal inhibitory concentration (IC

Indexed as

Drug CarriersAnimalsAntineoplastic Agents, PhytogenicCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug CompoundingFlavonoidsHumansHyaluronic AcidInhibitory Concentration 50Injections, IntravenousLung NeoplasmsMaleAntineoplastic Agents, Phytogenicbaohuoside IdidecyldimethylammoniumDrug CarriersFlavonoidsHyaluronic AcidMicellesPaclitaxelQuaternary Ammonium CompoundstocophersolanVitamin EantitumorBaohuoside Ihyaluronic acidmixed micellestargeting

Identifiers

PMID28155337
PMCPMC8244624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.