Evidence map›Paper›PMID 28155078›Full record

ReviewMolecular imaging and biology2017

The Promise of Molecular Imaging in the Study and Treatment of Infectious Diseases.

Sanjay K Jain

Abstract readReview
In one paragraph

Review in Molecular imaging and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 70 citations in OpenAlex.

  1. Diagnostic Performance of [Journal of clinical medicine · 2026
    Article
  2. Article
  3. Validation of Lung [Molecular imaging and biology · 2025
    Article
  4. Comparative Study of [Molecular imaging and biology · 2025
    Article
  5. Development of NovelACS pharmacology & translational science · 2025
    Article
  6. Article
  7. Biological Evaluation of d-[Journal of medicinal chemistry · 2024
    Article
  8. Article
  9. Review
  10. Preclinical evaluation of [European journal of nuclear medicine and molecular imaging · 2022
    Article
  11. Imaging joint infections using D-methyl-European journal of nuclear medicine and molecular imaging · 2022
    Article
  12. Review
  13. Review
  14. Cold Kit Labeling: The Future ofFrontiers in medicine · 2022
    Review
  15. Evaluation of 2-[Journal of fungi (Basel, Switzerland) · 2021
    Article
  16. Article
  17. ImagingScience translational medicine · 2021
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Sanjay K JainCenter for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, 1550 Orleans Street, CRB-II, Rm 1.09, Baltimore, MD, 21287, USA. sjain5@jhmi.edu.
Johns Hopkins University · US

Funding

Novel Imaging Tracers for Rapid and Noninvasive Assessment of Bacterial InfectionR01EB020539 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2014 to 2018
$3.6M
Novel imaging biomarkers to address fundamental controversies in TB pathogenesisDP2OD006492 · OD · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2009 to 2014
$2.9M
Molecular Imaging for Pulmonary Infections and InflammationR01HL131829 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2016 to 2018
$2.2M
NHLBI NIH HHS R01 HL131829NIBIB NIH HHS R01 EB020539NIH HHS DP2 OD006492
6 · The paper itself

Abstract

Infectious diseases are a major threat to humanity, and it is imperative that we develop imaging tools that aid in their study, facilitate diagnosis, and guide treatment. The alarming rise of highly virulent and multi-drug-resistant pathogens, their rapid spread leading to frequent global pandemics, fears of bioterrorism, and continued life-threatening nosocomial infections in hospitals remain as major challenges to health care in the USA and worldwide. Early diagnosis and rapid monitoring are essential for appropriate management and control of infections. Tomographic molecular imaging enables rapid, noninvasive visualization, localization, and monitoring of molecular processes deep within the body and offers several advantages over traditional tools used for the study of infectious diseases. Noninvasive, longitudinal assessments could streamline animal studies, allow unique insights into disease pathogenesis, and expedite clinical translation of new therapeutics. Since molecular imaging is already in common use in the clinic, it could also become a valuable tool for clinical studies, for patient care, for public health, and for enabling precision medicine for infectious diseases.

Indexed as

Molecular ImagingAnimalsCommunicable DiseasesDeveloping CountriesHumansPublic HealthTranslational Research, BiomedicalBacteriaInfluenzaMicrobiomeOptical imagingPETTB

Identifiers

PMID28155078
PMCPMC5407939
OpenAlexW2584360689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.