Evidence map›Paper›PMID 28154914›Full record

SynthesisInternational urogynecology journal2017

Laser therapy as a treatment modality for genitourinary syndrome of menopause: a critical appraisal of evidence.

Angamuthu Arunkalaivanan, Hervinder Kaur, Oseka Onuma

2 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International urogynecology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03833726 nacompletednot on this mapstarted 2019, after this paper: background citation

Light Emitting Diode for the Treatment of Genitourinary Syndrome of Menopause Associated With Hormonal Therapy for Treating Breast Cancer: Randomized Controlled Clinical Trial

TypeinterventionalSponsorCentro de Atenção ao Assoalho PélvicoRan2019 to 2023Enrolled77ConditionsAtrophy, Vaginal, Breast CancerArmsExperimental: LED group, Sham Comparator: Control
NCT04998578 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Comparison Of Aesthetic Techniques For Rejuvenation Of Genital Region: A Randomized Clinical Trial

TypeinterventionalSponsorCentro de Atenção ao Assoalho PélvicoRan2021 to 2024Enrolled112ConditionsLaxity, Skin, Skin Hyperpigmentation, Needlestick PunctureArmsComparison of aesthetic techniques
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Randomized clinical trial of vaginal microbiota in menopausal genitourinary syndrome using radiofrequency and topical estriol.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Trial
  6. Article
  7. Short-Term Superiority of Transvaginal COInternational journal of women's health · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Vaginal COBMC cancer · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The safety and efficacy of COInternational urogynecology journal · 2020
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Angamuthu ArunkalaivananWaikiki Specialist Centre, 221 Wilmott Drive, Waikiki, WA, 6169, Australia. asarun34@hotmail.com.ORCID http://orcid.org/0000-0002-5905-1158
Hervinder KaurArmadale Health Service, 3056 Albany Hway, Mount Nasura, WA, 6112, Australia.
Oseka OnumaThe Australian Centre for Pelvic and Vaginal Rejuvenation, 4 Robe Terrace, Medindie, SA, 5081, Australia.
Armadale Health ServiceUniversity of Wah · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interest in laser therapy as a nonhormonal option for the treatment of genitourinary syndrome of menopause (GSM) has increased. We conducted a systematic review of the use of laser therapy for the relief of GSM symptoms. Six electronic databases were searched and conference abstracts were searched manually from the introduction of laser therapy to the present date. The keywords used were: "genitourinary syndrome", "vulvovaginal atrophy", "postmenopausal symptoms", "laser therapy" and "fractional laser treatment". Of the 165 articles identified in the search, none was a randomized controlled trial. As a result, we included three observational studies without a control group and one case-control study that met our inclusion criteria. The total number of women included in the four studies was 220. The collated data suggest that laser therapy may be valuable as a nonhormonal therapeutic modality in the management of GSM. Higher quality of evidence from randomized controlled trials is required to establish the efficacy of laser treatment in the management of GSM.

Indexed as

MenopauseAtrophyCase-Control StudiesFemaleFemale Urogenital DiseasesHumansLasers, GasLaser TherapyObservational Studies as TopicSyndromeTreatment OutcomeVaginaVulvaAtrophic vaginitisFractional laser treatmentGenitourinary syndromeLaser therapyPostmenopausal symptomsVulvovaginal atrophy

Identifiers

PMID28154914
OpenAlexW2586011337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.