Evidence map›Paper›PMID 28154857›Full record

ArticleLab on a chip2017

A versatile platform for surface modification of microfluidic droplets.

Mingqiang Li, Weiqian Jiang, Zaozao Chen, Smruthi Suryaprakash, Shixian Lv, Zhaohui Tang, Xuesi Chen, Kam W Leong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lab on a chip, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Mingqiang LiDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA. kam.leong@columbia.edu.
Weiqian JiangDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA. kam.leong@columbia.edu.
Zaozao ChenDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA. kam.leong@columbia.edu.
Smruthi SuryaprakashDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA. kam.leong@columbia.edu.
Shixian LvKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China and University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
Zhaohui TangKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China.
Xuesi ChenKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China.
Kam W LeongDepartment of Biomedical Engineering, Columbia University, New York, NY 10027, USA. kam.leong@columbia.edu.ORCID 0000-0002-8133-4955
Columbia University · USChinese Academy of Sciences · CN

Funding

Interaction of Subchondral Bone and Articular Cartilage System with Skeletal MuscleUH3TR000505 · NCATS · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2014 to 2016
$3.6M
Oral Therapy for Hemophilia AR01HL109442 · NHLBI · UNIVERSITY OF FLORIDA · PI DANIELL, HENRY, HERZOG, ROLAND W. · 2011 to 2015
$3.5M
Circulatory system and integrated muscle tissue for drug and tissue toxicityUH2TR000505 · NCATS · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2012 to 2013
$2.1M
Overcoming Immunosenescence by Nanoparticle-Mediated ActivationR01AI096305 · NIAID · DUKE UNIVERSITY · PI ABRAHAM, SOMAN N, LEONG, KAM W · 2012 to 2016
$1.8M
A synthetic biology approach to analyze evolution of programmed bacterial deathR01GM110494 · NIGMS · DUKE UNIVERSITY · PI YOU, LINGCHONG · 2014 to 2017
$1.2M
NCATS NIH HHS UH2 TR000505NCATS NIH HHS UH3 TR000505NHLBI NIH HHS R01 HL109442NIAID NIH HHS R01 AI096305NIGMS NIH HHS R01 GM110494
6 · The paper itself

Abstract

To advance emulsion droplet technology, we synthesize functional derivatives of Pluronic F127 that can simultaneously act as surfactants and as reactive sites for droplet surface decoration. The amine-, carboxyl-, N-hydroxysuccinimide ester-, maleimide- and biotin-terminated Pluronic F127 allows ligand immobilization on single-emulsion or double-emulsion droplets via electrostatic adsorption, covalent conjugation or site-specific avidin-biotin interaction.

Indexed as

AvidinBiotinCell LineEmulsionsHumansMicrofluidic Analytical TechniquesPoloxamerSurface-Active AgentsSurface PropertiesAvidinBiotinEmulsionsPoloxamerSurface-Active Agents

Identifiers

PMID28154857
PMCPMC5328679
OpenAlexW2582590124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.