ArticleInternal medicine (Tokyo, Japan)2017
Bacterial Meningitis Caused by Hypervirulent Klebsiella pneumoniae Capsular Genotype K54 with Development of Granuloma-like Nodal Enhancement in the Brain during the Subacute Phase.
Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- Impact of an antimicrobial stewardship-based infection prevention bundle on postoperative central nervous system infection in a tertiary neurosurgery department: a quasi-experimental study.Frontiers in pharmacology · 2026Article
- Otitis Media Progressing to Community-Acquired Meningitis in Diabetic Patients: A Case Report of K2-ST375 hypervirulentInfection and drug resistance · 2024Article
- Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data.Life (Basel, Switzerland) · 2023Review
- Covert dissemination of pLVPK-like virulence plasmid in ST29-K54 Klebsiella pneumoniae: emergence of low virulence phenotype strains.Frontiers in cellular and infection microbiology · 2023Article
- Evaluation of a clinical pharmacist-led antimicrobial stewardship program in a neurosurgical intensive care unit: a pre-and post-intervention cohort study.Frontiers in pharmacology · 2023Article
- Treatment of Ventriculitis and Meningitis After Neurosurgery Caused by Carbapenem-ResistantInfection and drug resistance · 2023Review
- Article
- HypermucoviscousBMJ case reports · 2022Article
- Antimicrobial Susceptibility, Virulence, and Genomic Features of a Hypervirulent Serotype K2, ST65Antibiotics (Basel, Switzerland) · 2022Article
- Phenotypic and Molecular Characterization of K54-ST29 HypervirulentFrontiers in microbiology · 2022Article
- Iron Acquisition Systems of Gram-negative Bacterial Pathogens Define TonB-Dependent Pathways to Novel Antibiotics.Chemical reviews · 2021Review
- Rates of cerebrospinal fluid infection and the causative organisms following shunt procedures in Saudi Arabia. A retrospective study based on radiological findings.Saudi medical journal · 2020Article
- Longitudinal Analysis of Risk Factors for Clinical Outcomes ofInfection and drug resistance · 2020Article
- Clinical and Molecular Characteristics of Klebsiella pneumoniae Isolates Causing Bloodstream Infections in Japan: Occurrence of Hypervirulent Infections in Health Care.Journal of clinical microbiology · 2019Article
- Hypervirulent Klebsiella pneumoniae.Clinical microbiology reviews · 2019Review
- Article
- Capsular type K54, clonal group 29 and virulence plasmids: an analysis of K54 and non-K54 closely related isolates of Klebsiella pneumoniae.Epidemiology and infection · 2018Article
- Community acquiredGerms · 2018Article
- Structural and functional delineation of aerobactin biosynthesis in hypervirulentThe Journal of biological chemistry · 2018Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 72-year-old man was admitted to the emergency department due to coma. The cerebrospinal fluid cell count was 40,080 cells/μL, and Klebsiella pneumoniae was detected on culture. Stretching the bacterial colonies on an agar plate showed the formation of a viscous string with a length exceeding 5 mm, indicating hypervirulent K. pneumoniae (hv-KP). A genome analysis suggested hv-KP capsular genotype K54 with sequence type 29. Although no brain abscess was detected on contrast-enhanced computed tomography on Day 4 or on magnetic resonance imaging (MRI) on Day 7, contrast-enhanced MRI on Day 23 showed granuloma-like nodal enhancement on the surface of the left insula. Antibacterial therapy was continued until the enhancement disappeared on Day 40. MRI may help determine the duration required for antibacterial therapy. After six months, the patient was discharged and remained free from recurrence.
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Registered trials
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