Evidence map›Paper›PMID 28154179›Full record

ArticleThe Journal of biological chemistry2017

Antibody Neutralization of CXCL10

Pauline Bonvin, Franck Gueneau, Vanessa Buatois, Maud Charreton-Galby, Stanley Lasch, Marie Messmer, Urs Christen, Andrew D Luster, Zoë Johnson, Walter Ferlin and 3 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Common innate pathways to autoimmune disease.Clinical immunology (Orlando, Fla.) · 2020
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Pauline BonvinFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Franck GueneauFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Vanessa BuatoisFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Maud Charreton-GalbyFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Stanley LaschPharmazentrum Frankfurt/ZAFES Goethe University Hospital Frankfurt, Theodor-Stern Kai 7, 60590 Frankfurt am Main, Germany, and.
Marie MessmerPharmazentrum Frankfurt/ZAFES Goethe University Hospital Frankfurt, Theodor-Stern Kai 7, 60590 Frankfurt am Main, Germany, and.
Urs ChristenPharmazentrum Frankfurt/ZAFES Goethe University Hospital Frankfurt, Theodor-Stern Kai 7, 60590 Frankfurt am Main, Germany, and.
Andrew D Lusterthe Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114.
Zoë JohnsonFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Walter FerlinFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Marie Kosco-VilboisFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Amanda ProudfootFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland.
Nicolas FischerFrom Novimmune SA, chemin des Aulx 14, 1228 Plan-les-Ouates, Geneva, Switzerland, nfischer@novimmune.com.
Light Chain Bioscience (Switzerland) · CHUniversity Hospital Frankfurt · DEGoethe University Frankfurt · DEMassachusetts General Hospital · US

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
6 · The paper itself

Abstract

To improve our understanding of properties that confer successful inhibition of chemokines

Indexed as

AnimalsAntibodies, MonoclonalAntibodies, NeutralizingCells, CulturedChemokine CXCL10Chemotaxis, LeukocyteCricetinaeDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Endothelium, VascularFemaleGlycosaminoglycansHumansMiceMice, Inbred C57BLTissue DistributionAntibodies, MonoclonalAntibodies, NeutralizingChemokine CXCL10Glycosaminoglycanschemokinechemotaxisglycosaminoglycanmonoclonal antibodypharmacokineticstherapeutic inhibition

Identifiers

PMID28154179
PMCPMC5354510
OpenAlexW2583078041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.