ArticleJournal of the American Heart Association2017
Heritability of Vascular Structure and Function: A Parent-Child Study.
Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Heritability of carotid intima-media thickness and inflammatory factors of atherosclerosis in a Chinese population.Scientific reports · 2024Article
- Ideal Cardiovascular Health and Vascular Phenotype Associations in Mothers with Obesity and Their Six-Year-Old Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Accelerated Early Vascular Aging Among Adolescents With Obesity and/or Type 2 Diabetes Mellitus.Journal of the American Heart Association · 2020Article
- Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families.Atherosclerosis · 2019Article
- Article
- Cardiovascular Risk Factors Track From Mother to Child.Journal of the American Heart Association · 2018Article
- Fetal Antecedents of Cardiovascular Disease.Journal of the American Heart Association · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundUnderstanding the heritable contribution of vascular measures, from parent to offspring, may aid in risk stratification and atherosclerosis prevention efforts. We hypothesized that measures of vascular structure and function would be heritable in this cohort of parents and their adolescent offspring. METHODS AND
resultsHigh-resolution ultrasound scans of the brachial and carotid arteries were obtained in parents (n=558) and their offspring (n=369). Lumen diameter and flow-mediated dilation were measured in the brachial artery. Intima-media thickness, lumen diameter, incremental elastic modulus, diameter distensibility, and cross-sectional distensibility were measured, and carotid cross-sectional compliance was measured in the carotid artery. Carotid-radial pulse wave velocity was obtained using SphygmoCor
conclusionsThese data show that the majority of noninvasive measures of vascular structure and function are heritable, suggesting that measurement of these subclinical risk factors in parents may be helpful in assessing childhood risk for future cardiovascular disease.
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Registered trials
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