Evidence map›Paper›PMID 28154153›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

Jonathan J Wilde, Julie A Siegenthaler, Sharon Y R Dent, Lee A Niswander

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Complex functions of Gcn5 and Pcaf in development and disease.Biochimica et biophysica acta. Gene regulatory mechanisms · 2021
    Review
  9. Article
  10. Article
  11. Molecular Targets and Therapeutic Strategies in Spinocerebellar Ataxia Type 7.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonathan J WildeGraduate Program in Cell Biology, Stem Cells, and Development, University of Colorado Denver, Aurora, Colorado 80045, lee.niswander@ucdenver.edu wildej@mit.edu.ORCID 0000-0002-0800-8854
Julie A SiegenthalerDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado 80045, and.
Sharon Y R DentUniversity of Texas M.D. Anderson Cancer Center, Department of Epigenetics and Molecular Carcinogenesis, Smithville, Texas 78957.ORCID 0000-0002-4824-3269
Lee A NiswanderDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado 80045, and lee.niswander@ucdenver.edu wildej@mit.edu.
University of Colorado Anschutz Medical Campus · USThe University of Texas MD Anderson Cancer Center · US

Funding

Regulation of border specification in the developing forebrain by Gcn5-mediated rF31NS087692 · NINDS · UNIVERSITY OF COLORADO DENVER · PI WILDE, JONATHAN JUDSON · 2014 to 2015
$61k
NINDS NIH HHS F31 NS087692
6 · The paper itself

Abstract

Diencephalic defects underlie an array of neurological diseases. Previous studies have suggested that retinoic acid (RA) signaling is involved in diencephalic development at late stages of embryonic development, but its roles and mechanisms of action during early neural development are still unclear. Here we demonstrate that mice lacking enzymatic activity of the acetyltransferase GCN5 ((

Indexed as

AnimalsDiencephalonEnzyme ActivationFemaleHumansMiceMice, Inbred C57BLMice, KnockoutOrgan Sizep300-CBP-Associated Factorp300-CBP Transcription FactorsSignal TransductionTretinoinp300-CBP-Associated Factorp300-CBP Transcription FactorsTretinoindiencephalonGCN5KAT2Aretinoic acidTACC1thalamus

Identifiers

PMID28154153
PMCPMC5354317
OpenAlexW2585337119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.