Evidence map›Paper›PMID 28154098›Full record

ReviewCirculation research2017

Stroke Risk Factors, Genetics, and Prevention.

Amelia K Boehme, Charles Esenwa, Mitchell S V Elkind

5 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Circulation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 910 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
910citing papers in PubMed, 15 pooled it
63.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04505150 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Lowering Blood Pressure by Changing Lifestyle Through a Motivational Education Program: a Cluster RCT Study Protocol

TypeinterventionalSponsorOrganisation for Rural Community Development, BangladeshRan2020 to 2022Enrolled300ConditionsHigh Blood PressureArmsLifestyle changes, e.g., take part in regular exercise, quitting smoking, and reduce salt consumption
NCT04904172 unknown statusnot on this mapstarted 2020, after this paper: background citation

Effectiveness of NIRS (Near-Infrared Spectroscopy) in Indicating Cerebral Oxygenation at Acute Ischemic Stroke Patients Undergoing Intravenous Thrombolytic Therapy and / or Endovascular Thrombectomy

Typeobservational_patient_registrySponsorEge UniversityRan2020 to 2023Enrolled54ConditionsIschemic StrokeArmsMasimo O3 Regional Oximetry
NCT05120414 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effect of Ankle Strategy Exercises on Gait Parameters and Balance Confidence in Patients With Chronic Stroke

TypeinterventionalSponsorShifa Tameer-e-Millat UniversityRan2021 to 2021Enrolled36ConditionsStrokeArmsbalanace exercises, Balance Exercises plus Ankle strategy
NCT05306522 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effects of Telerehabilitation-Based Spinal Stabilization Exercises on Physical Activity Level and Fatigue in Chronic Stroke Patients

TypeinterventionalSponsorHacettepe UniversityRan2022 to 2024Enrolled30ConditionsStrokeArmsSpinal stabilization exercise
NCT05801575 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Efficacy of the CHM Teabag in Decreasing Stroke Risk Among Elderly People in Hong Kong: A Stepped Wedge Cluster Randomized Trial

TypeinterventionalSponsorHong Kong Baptist UniversityRan2023 to 2023Enrolled912ConditionsStroke, Risk Reduction, ElderlyArmsChinese Herbal Medicine (CHM) teabag
3 · Its place in the literature

Who cites it

910 citing papers in PubMed, 15 syntheses or guidelines pooled it, 1,866 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. P2YJournal of atherosclerosis and thrombosis · 2026
    Trial
  17. Trial
  18. Trial
  19. Article
  20. Article

850 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amelia K BoehmeFrom the Department of Epidemiology, Mailman School of Public Health (A.K.B., M.S.V.E.) and Department of Neurology, College of Physicians and Surgeons (A.K.B., C.E., M.S.V.E.), Columbia University, New York, NY.
Charles EsenwaFrom the Department of Epidemiology, Mailman School of Public Health (A.K.B., M.S.V.E.) and Department of Neurology, College of Physicians and Surgeons (A.K.B., C.E., M.S.V.E.), Columbia University, New York, NY.
Mitchell S V ElkindFrom the Department of Epidemiology, Mailman School of Public Health (A.K.B., M.S.V.E.) and Department of Neurology, College of Physicians and Surgeons (A.K.B., C.E., M.S.V.E.), Columbia University, New York, NY. mse13@columbia.edu.
Columbia University · US

Funding

NEUROEPIDEMIOLOGY TRAINING PROGRAMT32NS007153 · NINDS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GU, YIAN, WILLEY, JOSHUA ZEBADIAH · 1987 to 2023
$6.2M
NINDS NIH HHS T32 NS007153
6 · The paper itself

Abstract

Stroke is a heterogeneous syndrome, and determining risk factors and treatment depends on the specific pathogenesis of stroke. Risk factors for stroke can be categorized as modifiable and nonmodifiable. Age, sex, and race/ethnicity are nonmodifiable risk factors for both ischemic and hemorrhagic stroke, while hypertension, smoking, diet, and physical inactivity are among some of the more commonly reported modifiable risk factors. More recently described risk factors and triggers of stroke include inflammatory disorders, infection, pollution, and cardiac atrial disorders independent of atrial fibrillation. Single-gene disorders may cause rare, hereditary disorders for which stroke is a primary manifestation. Recent research also suggests that common and rare genetic polymorphisms can influence risk of more common causes of stroke, due to both other risk factors and specific stroke mechanisms, such as atrial fibrillation. Genetic factors, particularly those with environmental interactions, may be more modifiable than previously recognized. Stroke prevention has generally focused on modifiable risk factors. Lifestyle and behavioral modification, such as dietary changes or smoking cessation, not only reduces stroke risk, but also reduces the risk of other cardiovascular diseases. Other prevention strategies include identifying and treating medical conditions, such as hypertension and diabetes, that increase stroke risk. Recent research into risk factors and genetics of stroke has not only identified those at risk for stroke but also identified ways to target at-risk populations for stroke prevention.

Indexed as

Life StyleBrain IschemiaClinical Trials as TopicDiabetes MellitusDietGenetic Predisposition to DiseaseHumansHypertensionRisk FactorsSmokingStrokecerebrovascular disordersepidemiologyrisk factorsstroketransient ischemic attack

Identifiers

PMID28154098
PMCPMC5321635
OpenAlexW2585605401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.