Evidence map›Paper›PMID 28154087›Full record

ArticleHaematologica2017

Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.

Julia Schanda, Chun-Wei Lee, Katharina Wohlan, Uta Müller-Kuller, Hana Kunkel, Isabell Quagliano-Lo Coco, Stefan Stein, Alexander Metz, Joachim Koch, Jörn Lausen and 8 more

Open access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  5. Gene Transcription as a Therapeutic Target in Leukemia.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Julia SchandaInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Chun-Wei LeeDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
Katharina WohlanDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
Uta Müller-KullerInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Hana KunkelInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Isabell Quagliano-Lo CocoInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Stefan SteinInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Alexander MetzInstitute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany.
Joachim KochInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Jörn LausenInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Uwe PlatzbeckerDepartment of Hematology, Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, Dresden, Germany.
Hind MedyoufInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany.
Michael HeuserDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
Matthias EderDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
Manuel GrezInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany grez@gsh.uni-frankfurt.de.
Michaela ScherrDepartment of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
Christian WichmannInstitute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Georg Speyer Haus · DEMedizinische Hochschule Hannover · DEHeinrich Heine University Düsseldorf · DEUniversity Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCell ProliferationCore Binding Factor Alpha 2 SubunitDisease Models, AnimalGene ExpressionHumansMiceOncogene Proteins, FusionProtein MultimerizationRUNX1 Translocation Partner 1 ProteinXenograft Model Antitumor AssaysAntineoplastic AgentsCore Binding Factor Alpha 2 SubunitOncogene Proteins, FusionRUNX1 protein, humanRUNX1T1 protein, humanRUNX1 Translocation Partner 1 Protein

Identifiers

PMID28154087
PMCPMC5685283
OpenAlexW2585665028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.