Evidence map›Paper›PMID 28153957›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2017

Localization of Unknown Primary Site with

Yusuf Menda, Thomas M O'Dorisio, James R Howe, Michael Schultz, Joseph S Dillon, David Dick, G Leonard Watkins, Timothy Ginader, David L Bushnell, John J Sunderland and 3 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01619865 (Safety & Efficacy of 68Ga-DOTA-tyr3-Octreotide PET/CT in Diagnosis, Staging & Measurement of Response to Treatment in Patients With Somatostatin Receptor Positive Tumors), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01619865 phase1 / phase2completednot on this map

Safety & Efficacy of 68Ga-DOTA-tyr3-Octreotide PET/CT in Diagnosis, Staging & Measurement of Response to Treatment in Patients With Somatostatin Receptor Positive Tumors: Comparison to Octreoscan Plus High-Resolution, Contrast Enhanced CT.

TypeinterventionalSponsorSue O'DorisioRan2012 to 2017Enrolled223ConditionsNeuroendocrine Tumors, Carcinoid Tumors, Neuroblastoma, MedulloblastomaArms68Ga-DOTATOC PET/CT
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2017
    Pooled it
  3. Article
  4. Review
  5. Dual PET Imaging with [Current oncology (Toronto, Ont.) · 2025
    Article
  6. Review
  7. The University of Iowa Neuroendocrine Tumor Clinic.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Nuclear Imaging of Neuroendocrine Tumors.Surgical oncology clinics of North America · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yusuf MendaDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa yusuf-menda@uiowa.edu.
Thomas M O'DorisioDepartment of Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
James R HoweDepartment of Surgery, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Michael SchultzDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Joseph S DillonDepartment of Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
David DickDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
G Leonard WatkinsDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Timothy GinaderHolden Comprehensive Cancer Center, University of Iowa Carver College of Medicine, Iowa City, Iowa.
David L BushnellDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
John J SunderlandDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Gideon K D ZambaDepartment of Biostatistics, University of Iowa College of Public Health, Iowa City, Iowa; and.
Michael GrahamDepartment of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
M Sue O'DorisioDepartment of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, Iowa.

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Project 4: New Approaches to Improving the Effectiveness of Radionuclide Targeted Treatments in Neuroendocrine TumorsP50CA174521 · NCI · UNIVERSITY OF IOWA · PI ODORISIO, THOMAS · 2015 to 2021
$13.2M
NCI NIH HHS P50 CA174521
6 · The paper itself

Abstract

Localization of the site of the unknown primary tumor is critical for surgical treatment of patients presenting with neuroendocrine tumor (NET) with metastases.

Indexed as

Organometallic CompoundsAdultAgedFemaleHumansMaleMiddle AgedNeoplasms, Unknown PrimaryNeuroendocrine TumorsObserver VariationOctreotidePositron Emission Tomography Computed TomographyRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificityYoung AdultGa(III)-DOTATOCOctreotideOrganometallic CompoundsRadiopharmaceuticals68Ga-DOTATOCneuroendocrineneuroendocrine tumorPET/CTunknown primary

Identifiers

PMID28153957
PMCPMC5493006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.