Evidence map›Paper›PMID 28153919›Full record

ArticlePlant physiology2017

Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.

José-Antonio Pedroza-García, Christelle Mazubert, Ivan Del Olmo, Mickael Bourge, Séverine Domenichini, Rémi Bounon, Zakia Tariq, Etienne Delannoy, Manuel Piñeiro, José A Jarillo and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Plant physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. LUMINIDEPENDENS orchestrates global transcriptional repression inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Genes · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. A Journey to the Core of the Plant Cell Cycle.International journal of molecular sciences · 2022
    Review
  9. Article
  10. Article
  11. A Mutation in DNA Polymerase α RescuesInternational journal of molecular sciences · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Plant DNA Polymerases.International journal of molecular sciences · 2019
    Review
  16. Review
  17. SOG1 activator and MYB3R repressors regulate a complex DNA damage network inProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

José-Antonio Pedroza-GarcíaInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Christelle MazubertInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Ivan Del OlmoInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).ORCID 0000-0002-5169-4335
Mickael BourgeInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Séverine DomenichiniInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Rémi BounonInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Zakia TariqInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Etienne DelannoyInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Manuel PiñeiroInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).ORCID 0000-0002-4640-6511
José A JarilloInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).ORCID 0000-0002-2963-7641
Catherine BergouniouxInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Moussa BenhamedInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.).
Cécile RaynaudInstitute of Plant Sciences Paris-Saclay IPS2, CNRS, INRA, Université Paris-Sud, Université Évry, Université Paris-Saclay, 91405 Orsay, France (J.A.P.-G., C.M., S.D., R.B., Z.T., E.D., C.B., M.B., C.R.); cecile.raynaud@u-psud.fr.ORCID 0000-0002-5231-8120
Université Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Faithful transmission of the genetic information is essential in all living organisms. DNA replication is therefore a critical step of cell proliferation, because of the potential occurrence of replication errors or DNA damage when progression of a replication fork is hampered causing replicative stress. Like other types of DNA damage, replicative stress activates the DNA damage response, a signaling cascade allowing cell cycle arrest and repair of lesions. The replicative DNA polymerase ε (Pol ε) was shown to activate the S-phase checkpoint in yeast in response to replicative stress, but whether this mechanism functions in multicellular eukaryotes remains unclear. Here, we explored the genetic interaction between Pol ε and the main elements of the DNA damage response in Arabidopsis (

Indexed as

DNA ReplicationArabidopsisArabidopsis ProteinsCell Cycle CheckpointsDNA, PlantDNA Polymerase IIGene Expression ProfilingGene Expression Regulation, PlantGene OntologyHydroxyureaMicroscopy, FluorescenceModels, GeneticMutationNucleic Acid Synthesis InhibitorsPlants, Genetically ModifiedReverse Transcriptase Polymerase Chain ReactionArabidopsis ProteinsDNA, PlantDNA Polymerase IIHydroxyureaNucleic Acid Synthesis Inhibitors

Identifiers

PMID28153919
PMCPMC5338674
OpenAlexW2584105067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.