ArticleMolecular & cellular proteomics : MCP2017
An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways.
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Article in Molecular & cellular proteomics : MCP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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52citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
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Who cites it
52 citing papers in PubMed, 71 citations in OpenAlex.
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- Inhibition of SREBP-1c rescues hepatic CYP7B1 expression and bile acid synthesis in malnourished mice.American journal of physiology. Gastrointestinal and liver physiology · 2025Article
- Disruption of oocyte SUMOylation impacts critical regulatory processes during folliculogenesis in mice†.Biology of reproduction · 2025Article
- In-depth and high-throughput spatial proteomics for whole-tissue slice profiling by deep learning-facilitated sparse sampling strategy.Cell discovery · 2025Article
- Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Molecularly-guided spatial proteomics captures single-cell identity and heterogeneity of the nervous system.bioRxiv : the preprint server for biology · 2025Article
- Biological sex, microglial signaling pathways, and radiation exposure shape cortical proteomic profiles and behavior in mice.Brain, behavior, & immunity - health · 2025Article
- A Systematic Review of Extracellular Matrix-Related Alterations in Parkinson's Disease.Brain sciences · 2024Review
- Inferring Bladder Cancer Evolution from Mucosal field Effects by Whole-Organ Spatial Mutational, Proteomic, and Metabolomic Mapping.Research square · 2024Article
- Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.Nature cell biology · 2024Article
- CAMKV Kinase Signaling Is a Novel Therapeutic Avenue with Prognostic Relevance in Neuroblastoma.bioRxiv : the preprint server for biology · 2024Article
- Disruption of CFAP418 interaction with lipids causes widespread abnormal membrane-associated cellular processes in retinal degenerations.JCI insight · 2024Article
- Mass spectrometry-based proteomic characterization of the middle-aged mouse brain for animal model research of neuromuscular diseases.European journal of translational myology · 2023Article
- A Mouse Model to Test Novel Therapeutics for Parkinson's Disease: an Update on the Thy1-aSyn ("line 61") Mice.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- In-depth mapping of protein localizations in whole tissue by micro-scaffold assisted spatial proteomics (MASP).Nature communications · 2022Article
- Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor impairment and cortical dysfunction, independent of protein aggregation.Human molecular genetics · 2022Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 4 countries.
Sung Yun JungFrom the ‡Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77003; syjung@bcm.edu jqin@bcm.edu.ORCID 0000-0003-1521-7977
Jong Min ChoiFrom the ‡Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77003.
Maxime W C Rousseaux**Department of Molecular and Human Genetics, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77003.
Anna MalovannayaFrom the ‡Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77003.
Jean J Kim‡‡Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030.
Joachim Kutzera§§Biosystems Data Analysis, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Yi WangFrom the ‡Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77003.
Yin Huang¶¶State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing, China.
Weimin Zhu¶¶State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing, China.
Suman Maity‖‖Advanced Technology Core. Baylor College of Medicine, Houston, Texas 77030; and.
Huda Yahya Zoghbi**Department of Molecular and Human Genetics, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, Texas 77003.
Jun QinFrom the ‡Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77003; syjung@bcm.edu jqin@bcm.edu.
Baylor College of Medicine · USBeijing Proteome Research Center · CNHoward Hughes Medical Institute · USNetherlands Institute for Neuroscience · NLNeurological Research Institute · US
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8MMOLECULAR STUDIES OF SPINOCEREBELLAR ATAXIS TYPE IR37NS027699 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI ZOGHBI, HUDA Y · 2015 to 2021
$2.8MCIHRHoward Hughes Medical InstituteNCI NIH HHS P30 CA125123NICHD NIH HHS U54 HD083092NINDS NIH HHS R37 NS027699
Abstract
Here, we present a mouse brain protein atlas that covers 17 surgically distinct neuroanatomical regions of the adult mouse brain, each less than 1 mm
Indexed as
AnimalsBrain MappingDisease Models, AnimalGene Expression RegulationHumansMiceParkinson DiseasePars CompactaProteomeProteomicsVentral Tegmental AreaProteome
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.