Evidence map›Paper›PMID 28153357›Full record

ArticleBioorganic & medicinal chemistry letters2017

Bidentate iminodiacetate modified dendrimer for bone imaging.

Lara Pes, Young Kim, Ching-Hsuan Tung

Abstract read
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lara PesMolecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, NY 10021, USA.
Young KimMolecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, NY 10021, USA; Department of Pathology, Chonnam National University Medical School, 671, Jebongno, Dong-Gu, Gwangju 501-757, Republic of Korea.
Ching-Hsuan TungMolecular Imaging Innovations Institute, Department of Radiology, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address: cht2018@med.cornell.edu.

Funding

Sound excitable drugsR01GM094880 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI TUNG, CHING-HSUAN · 2010 to 2014
$1.2M
NIGMS NIH HHS R01 GM094880
6 · The paper itself

Abstract

A new dendrimer probe was designed for bone imaging. Bidentate iminodiacetate groups were introduced to the probe to obtain strong bind to bones. The assembled dendrimeric probe, with four iminodiacetate moieties and a fluorescent tag, displayed good selectivity to hydroxyapatite, calcium oxalate and calcium phosphate salts. In mice, the probe offered vivid skeletal details after intravenous delivery.

Indexed as

Bone and BonesDiagnostic ImagingAdministration, IntravenousAnimalsDendrimersFluorescent DyesImino AcidsMiceMolecular StructurePolylysineDendrimersFluorescent DyesImino AcidsPolylysineBoneDendrimerFluorescence imagingHydroxyapatiteIminodiacetate

Identifiers

PMID28153357
PMCPMC5328641

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.