Evidence map›Paper›PMID 28153100›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2017

Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.

Anastassia Karageorgis, Michaël Claron, Romain Jugé, Caroline Aspord, Fabien Thoreau, Claire Leloup, Jérôme Kucharczak, Joël Plumas, Maxime Henry, Amandine Hurbin and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. The role of integrins in melanoma: a review.International journal of dermatology · 2020
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Synthesis and photophysical studies of a multivalent photoreactive RuBeilstein journal of organic chemistry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Anastassia KarageorgisINSERM U1209, Institut Albert Bonniot, 38706 La Tronche, France; Université Grenoble Alpes, 38000 Grenoble, France.
Michaël ClaronUniversité Grenoble Alpes, 38000 Grenoble, France; CNRS UMR 5250, ICMG FR2607, 38000 Grenoble, France.
Romain JugéMolecular Biology of the Cell Laboratory (LBMC), Ecole Normale Supérieure de Lyon, UMR 5239 CNRS - UCBL - ENS Lyon, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.
Caroline AspordUniversité Grenoble Alpes, 38000 Grenoble, France; EMR EFS-UGA-INSERM U1209- CNRS, Immunobiology and Immunotherapy of Chronic Diseases, 38706 La Tronche, France; EFS Rhone-Alpes, R&D Laboratory, 38701 La Tronche, France.
Fabien ThoreauINSERM U1209, Institut Albert Bonniot, 38706 La Tronche, France; Université Grenoble Alpes, 38000 Grenoble, France; CNRS UMR 5250, ICMG FR2607, 38000 Grenoble, France.
Claire LeloupUniversité Grenoble Alpes, 38000 Grenoble, France; EMR EFS-UGA-INSERM U1209- CNRS, Immunobiology and Immunotherapy of Chronic Diseases, 38706 La Tronche, France; EFS Rhone-Alpes, R&D Laboratory, 38701 La Tronche, France.
Jérôme KucharczakMolecular Biology of the Cell Laboratory (LBMC), Ecole Normale Supérieure de Lyon, UMR 5239 CNRS - UCBL - ENS Lyon, 46 Allée d'Italie, 69364 Lyon Cedex 07, France.
Joël PlumasUniversité Grenoble Alpes, 38000 Grenoble, France; EMR EFS-UGA-INSERM U1209- CNRS, Immunobiology and Immunotherapy of Chronic Diseases, 38706 La Tronche, France; EFS Rhone-Alpes, R&D Laboratory, 38701 La Tronche, France.
Maxime HenryINSERM U1209, Institut Albert Bonniot, 38706 La Tronche, France; Université Grenoble Alpes, 38000 Grenoble, France.
Amandine HurbinINSERM U1209, Institut Albert Bonniot, 38706 La Tronche, France; Université Grenoble Alpes, 38000 Grenoble, France.
Pascal VerdiéCNRS UMR 5247, Institut des Biomolécules Max Mousseron IBMM, 34095 Montpellier, France.
Jean MartinezCNRS UMR 5247, Institut des Biomolécules Max Mousseron IBMM, 34095 Montpellier, France.
Gilles SubraCNRS UMR 5247, Institut des Biomolécules Max Mousseron IBMM, 34095 Montpellier, France.
Pascal DumyCNRS UMR 5250, ICMG FR2607, 38000 Grenoble, France; CNRS UMR 5247, Institut des Biomolécules Max Mousseron IBMM, 34095 Montpellier, France.
Didier BoturynUniversité Grenoble Alpes, 38000 Grenoble, France; CNRS UMR 5250, ICMG FR2607, 38000 Grenoble, France.
Abdel AouacheriaMolecular Biology of the Cell Laboratory (LBMC), Ecole Normale Supérieure de Lyon, UMR 5239 CNRS - UCBL - ENS Lyon, 46 Allée d'Italie, 69364 Lyon Cedex 07, France; Institut des Sciences de l'Evolution de Montpellier (ISEM), UMR 5554, Université de Montpellier, CNRS, IRD, EPHE, Place Eugène Bataillon, 34095 Montpellier, France. Electronic address: jean-luc.coll@univ-grenoble-alpes.fr.
Jean-Luc CollINSERM U1209, Institut Albert Bonniot, 38706 La Tronche, France; Université Grenoble Alpes, 38000 Grenoble, France. Electronic address: abdel.aouacheria@umontpellier.fr.
Centre National de la Recherche Scientifique · FRUniversité Grenoble Alpes · FRInserm · FRInstitut des Biomolécules Max Mousseron · FRInstitut pour l'avancée des biosciences · FRÉcole Normale Supérieure de Lyon · FRInstitut de Chimie Moléculaire de Grenoble · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is a highly metastatic and deadly form of cancer. Invasive melanoma cells overexpress integrin α

Indexed as

AnimalsAntineoplastic AgentsApoptosisbcl-2-Associated X ProteinCell Line, TumorCell ProliferationDisease Models, AnimalHumansMelanomaMiceMice, KnockoutNeovascularization, PathologicPeptide FragmentsTumor BurdenXenograft Model Antitumor AssaysAntineoplastic Agentsbcl-2-Associated X ProteinPeptide FragmentsBAXpore-forming peptidesRGDtargeted delivery

Identifiers

PMID28153100
PMCPMC5368406
OpenAlexW2579639856

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.