Evidence map›Paper›PMID 28152649›Full record

ArticlePharmaceutical biology2017

Anti-inflammatory, anti-cholinergic and cytotoxic effects of Sida rhombifolia.

Siau Hui Mah, Soek Sin Teh, Gwendoline Cheng Lian Ee

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 63 citations in OpenAlex.

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  11. Protective Effects ofEvidence-based complementary and alternative medicine : eCAM · 2022
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  12. Physical and Tensile Properties of HandmadeInternational journal of biomaterials · 2020
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  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Siau Hui Maha School of Biosciences, Taylor's University , Subang Jaya , Selangor , Malaysia.
Soek Sin Tehb Department of Engineering and Processing , Malaysian Palm Oil Board , Kajang , Selangor , Malaysia.
Gwendoline Cheng Lian Eec Department of Chemistry, Faculty of Science , Universiti Putra Malaysia , Serdang , Selangor , Malaysia.
Malaysian Palm Oil Board · MYTaylor's University · MYUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextSida (Malvaceae) has been used as a traditional remedy for the treatment of diarrhoea, malarial, gastrointestinal dysentery, fevers, asthma and inflammation.

objectivesThis study evaluates the anti-inflammatory, cytotoxic and anti-cholinergic activities of Sida rhombifolia Linn. whole plant for the first time. MATERIALS AND

methodsS. rhombifolia whole plant was extracted by n-hexane, ethyl acetate and methanol using Soxhlet apparatus. The plant extracts were evaluated for their antioxidant (DPPH, FIC and FRAP), anti-inflammatory (NO and protein denaturation inhibitions), cytotoxic (MTT) and anti-cholinesterase (AChE) properties in a range of concentrations to obtain IC RESULTS AND DISCUSSION: The ethyl acetate extract exhibited the most significant antioxidant activities by scavenging DPPH radicals and ferrous ions with EC

conclusionsThe present study revealed that the n-hexane extract possessed relatively high pharmacological activities in anti-inflammation, cytotoxicity and anti-cholinesterase assays. Thus, further work on the detail mechanism of the bioactive phytochemicals which contribute to the biological properties are strongly recommended.

Indexed as

MalvaceaeAnimalsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsArtemiaCholinergic AntagonistsCholinesterase InhibitorsMicePhenolsPlant ExtractsRAW 264.7 CellsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsCholinergic AntagonistsCholinesterase InhibitorsPhenolsPlant ExtractsAcetylcholinesterasearrowleaf sidabrine shrimpMTTnitric oxideprotein denaturation

Identifiers

PMID28152649
PMCPMC6130616
OpenAlexW2583373704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.