ArticleInternational journal of surgery case reports2017
Pancreatitis, panniculitis and polyarthritis (PPP-) syndrome caused by post-pancreatitis pseudocyst with mesenteric fistula. Diagnosis and successful surgical treatment. Case report and review of literature.
Article in International journal of surgery case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- MRI features of pancreatitis, panniculitis, polyarthritis and the fourth p: The "polka dot sign." A case series and imaging review.Radiology case reports · 2026Article
- Case report: Pancreatitis-associated polyarthritis, panniculitis, and bone infarcts in a patient with alcohol use disorder.Acta radiologica open · 2026Article
- Pancreatitis, panniculitis, polyarthritis syndrome as an initial manifestation of metastatic pancreatic cancer in a breast cancer patient: Importance of early recognition and multidisciplinary management: A case report.SAGE open medical case reports · 2026Article
- Pancreatitis, panniculitis, and polyarthritis syndrome presentation, diagnosis, and management.Journal of surgical case reports · 2025Article
- Fatal case of pancreatic panniculitis and polyarthritis due to pancreatic neuroendocrine tumor: a case report and review of literature.Rheumatology international · 2025Review
- Arthritis with chronic pancreatitis-do not forget pancreatitis, panniculitis and polyarthritis (PPP) syndrome.Oxford medical case reports · 2025Article
- Understanding the PPP Syndrome: A Rare Combination of Pancreatitis, Panniculitis, and Polyarthritis.Advanced biomedical research · 2025Article
- Rare complications of ERCP-pancreatitis, panniculitis, and polyarthritis syndromeand multifocal osteomyelitis.BJR case reports · 2025Article
- A 50-year-old patient with pancreatitis revealing pancreatitis, panniculitis, and polyarthritis syndrome-a case report and review of the literature.Wiener medizinische Wochenschrift (1946) · 2024Review
- Painful nodules on the lower legs.JAAD case reports · 2024Article
- Pancreatitis, Panniculitis, and Polyarthritis Syndrome in Two Patients: A Case Series and Literature Review.Cureus · 2024Article
- Pancreatitis, panniculitis and polyarthritis (PPP) syndrome.BMJ case reports · 2023Article
- Pancreatitis, panniculitis and polyarthralgia syndrome: A rare complication of pancreatic pathology.Radiology case reports · 2023Article
- Pancreatitis, Panniculitis, and Polyarthritis (PPP) Syndrome in the Setting of Severe Acute Pancreatitis.Cureus · 2023Article
- Pancreatic panniculitis and polyarthropathy due to undifferentiated pleomorphic sarcoma.JAAD case reports · 2022Article
- Subcutaneous and Intraosseous Fat Necrosis Associated with Chronic Pancreatitis.Medicina (Kaunas, Lithuania) · 2022Article
- Pancreatitis, Panniculitis, and Polyarthritis Syndrome with a Fatal Course.Annals of dermatology · 2022Article
- Clinical characteristics, treatment, and outcome of pancreatitis, panniculitis, and polyarthritis syndrome: a case-based review.Clinical rheumatology · 2021Review
- Pancreatitis, panniculitis, and polyarthritis syndrome complicated with terminal pancreatic adenocarcinoma managed with intra-articular knee aspiration, intra-articular lidocaine and corticosteroid injection, and decompression of panniculitis: A case report.Journal of general and family medicine · 2021Article
- Pancreatic panniculitis and elevated serum lipase in metastasized acinar cell carcinoma of the pancreas: A case report and review of literature.World journal of clinical cases · 2020Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPancreatitis, panniculitis and polyarthritis syndrome is a very rare extra-pancreatic complication of pancreatic diseases. PRESENTATION OF CASE: While in most cases this syndrome is caused by acute or chronic pancreatitis, we report a case of a 62-year-old man presenting with extensive intraosseous fat necrosis, polyarthritis and panniculitis caused by a post-pancreatitis pseudocyst with a fistula to the superior mesenteric vein and extremely high blood levels of lipase. This became symptomatic 2.5 years after an episode of acute pancreatitis and as in most cases abdominal symptoms were absent. Treatment by surgical resection of the pancreatic head with the pseudocyst and mesenteric fistula led to complete remission of all symptoms. DISCUSSION: A review of the literature revealed that all publications are limited to case reports. Most authors hypothesize that an unspecific damage can cause a secretion of pancreatic enzymes to the bloodstream leading to a systemic lipolysis and fat tissue necrosis, especially of subcutaneous tissue, bone marrow, inducing panniculitis, polyarthritis and osteonecrosis. Even if caused by an acute pancreatitis abdominal symptoms are often mild or absent in most cases leading to misdiagnosis and poor prognosis.
conclusionWhile symptomatic treatment with NSAR and cortisone showed poor to moderate response, causal treatment can be successful depending on the underlying pancreatic disease.
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