ArticleInternational journal of surgery case reports2017
Aggregatibacter aphrophilus infective endocarditis confirmed by broad-range PCR diagnosis: A case report.
Article in International journal of surgery case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Antineutrophil cytoplasmic antibodies in infective endocarditis: a case report and systematic review of the literature.Clinical rheumatology · 2022Pooled it
- Facet joint arthritis as the presenting symptom for culture-negative Aggregatibacter aphrophilus native valve endocarditis in a patient without known cardiac disease: a case report.BMC infectious diseases · 2025Article
- Predicting bacterial infection risk in patients with ANCA-associated vasculitis in southwest China: development of a new nomogram.Clinical rheumatology · 2022Article
- Case Report: The First Case of Bloodstream Infection Complicated with Psoas Abscess and Pulmonary Infection Caused byInfection and drug resistance · 2022Article
- A rare cause of culture negative bioprosthetic valve endocarditis: a case report ofEuropean heart journal. Case reports · 2021Article
- Antineutrophil cytoplasmic antibody-positive infective endocarditis complicated by acute kidney injury: a case report and literature review.The Journal of international medical research · 2020Review
- Proteinase 3-antineutrophil cytoplasmic antibody-positive necrotizing crescentic glomerulonephritis complicated by infectious endocarditis: a case report.Journal of medical case reports · 2019Article
- Article
- Challenges and Insights inArchivos peruanos de cardiologia y cirugia cardiovascularReview
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAggregatibacter aphrophilus is a rare cause of infective endocarditis. This pathogen is difficult to identify with common culture methods, which can lead to incorrect diagnosis and treatment. PRESENTATION OF CASE: A 72-year-old woman was admitted to a community hospital with a persistent high fever and deteriorating renal function. Based on negative blood culture and positive serum proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA), acute renal failure associated with ANCA-rerated vasculitis was initially suspected. However, the patient developed heart failure soon afterward; echocardiography showed mitral insufficiency with mobile vegetation attached to the mitral valve, indicating infective endocarditis. After transfer to our hospital, the patient underwent mitral valve repair. Broad-range polymerase chain reaction (br-PCR) and sequencing identified Aggregatibacter aphrophilus in the excised vegetation. The patient had a good postoperative course, with recovery of renal function.
conclusionA rare disease, Aggregatibacter aphrophilus infective endocarditis was successfully treated with surgical repair and appropriate antibiotic therapy. To avoid misdiagnosis, br-PCR testing should be performed in patients with blood culture-negative endocarditis.
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