Evidence map›Paper›PMID 28152382›Full record

ArticleVirology2017

Statoviruses, A novel taxon of RNA viruses present in the gastrointestinal tracts of diverse mammals.

Andrew B Janowski, Siddharth R Krishnamurthy, Efrem S Lim, Guoyan Zhao, Jason M Brenchley, Dan H Barouch, Chrissie Thakwalakwa, Mark J Manary, Lori R Holtz, David Wang

Open access · hybridAbstract read
In one paragraph

Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Global Organization and Proposed Megataxonomy of the Virus World.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  8. Infection and Propagation of Astrovirus VA1 in Cell Culture.Current protocols in microbiology · 2019
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Andrew B JanowskiDepartment of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
Siddharth R KrishnamurthyDepartment of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Efrem S LimDepartment of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Guoyan ZhaoDepartment of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Jason M BrenchleyLab of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Dan H BarouchCenter for Virology and Vaccine Research Beth Israel Deaconess Medical Center, Boston, MA, USA; Ragon Institute of MGH, MIT, and Harvard, Boston, MA, USA.
Chrissie ThakwalakwaDepartment of Community Health, College of Medicine, University of Malawi, Blantyre 3, Malawi.
Mark J ManaryDepartment of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
Lori R HoltzDepartment of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
David WangDepartment of Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. Electronic address: davewang@wustl.edu.
Washington University in St. Louis · USBeth Israel Deaconess Medical Center · USNational Institutes of Health · USUniversity of Malawi · MW

Funding

Mechanisms of Immune Activation and Disease Progression in Animal ModelsZIAAI001029 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BRENCHLEY, JASON · 2009 to 2025
$28.2M
Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Pediatric Infectious Diseases and Immunity Training ProgramT32AI106688 · NIAID · WASHINGTON UNIVERSITY · PI Megan Anne Cooper, DAVID HUNSTAD · 2014 to 2026
$1.9M
THE VIROME AND MICROBIOME IN HEALTH AND BK DISEASE OF KIDNEY TRANSPLANT PATIENTSK99DK107923 · NIDDK · WASHINGTON UNIVERSITY · PI LIM, EFREM · 2016 to 2016
$92k
NIAID NIH HHS T32 AI007172NIAID NIH HHS T32 AI106688NIDDK NIH HHS K99 DK107923
6 · The paper itself

Abstract

Next-generation sequencing has expanded our understanding of the viral populations that constitute the mammalian virome. We describe a novel taxon of viruses named Statoviruses, for Stool associated Tombus-like viruses, present in multiple metagenomic datasets. These viruses define a novel clade that is phylogenetically related to the RNA virus families Tombusviridae and Flaviviridae. Five distinct statovirus types were identified in human, macaque, mouse, and cow gastrointestinal tract samples. The prototype genome, statovirus A, was frequently identified in macaque stool samples from multiple geographically distinct cohorts. Another genome, statovirus C1, was discovered in a stool sample from a human child with fever, cough, and rash. Further experimental data will clarify whether these viruses are infectious to mammals or if they originate from another source present in the mammalian gastrointestinal tract.

Indexed as

AnimalsBase SequenceCattleComputational BiologyFecesGastrointestinal TractGenome, ViralGeographyHigh-Throughput Nucleotide SequencingHumansMacaca mulattaMacaca nemestrinaMicePhylogenyRNA, ViralRNA VirusesRNA, ViralFlaviviridaeStatovirusesTombusviridaeViral discoveryVirome

Identifiers

PMID28152382
PMCPMC5515247
OpenAlexW2580231826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.