Evidence map›Paper›PMID 28152305›Full record

ArticleMolecules and cells2017

Concurrent Hypermethylation of

Hao Wang, Xiang-Long Duan, Xiao-Li Qi, Lei Meng, Yi-Song Xu, Tong Wu, Peng-Gao Dai

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 42 citations in OpenAlex.

  1. miR-452-3p Targets Adenomatous Polyposis Coli to Regulate the Malignant Phenotypes and Prognosis of Esophageal Cancer.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026
    Article
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  8. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
    Review
  9. Article
  10. Review
  11. Promoter methylation analysis ofAsian biomedicine : research, reviews and news · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Concurrent Evaluation of the Expression and Methylation ofIranian journal of medical sciences · 2021
    Article
  17. Article
  18. Targeting Wnt Signaling for the Treatment of Gastric Cancer.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hao WangNational Engineering Research Center for Miniaturized Detection Systems, School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Xiang-Long DuanSecond Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Xiao-Li QiNational Engineering Research Center for Miniaturized Detection Systems, School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Lei MengNational Engineering Research Center for Miniaturized Detection Systems, School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Yi-Song XuNational Engineering Research Center for Miniaturized Detection Systems, School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Tong WuNational Engineering Research Center for Miniaturized Detection Systems, School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Peng-Gao DaiNational Engineering Research Center for Miniaturized Detection Systems, School of Life Sciences, Northwest University, Xi'an, Shaanxi, China.
Northwest University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNYulin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant hypermethylation of Wnt antagonists has been observed in gastric cancer. A number of studies have focused on the hypermethylation of a single Wnt antagonist and its role in regulating the activation of signaling. However, how the Wnt antagonists interacted to regulate the signaling pathway has not been reported. In the present study, we systematically investigated the methylation of some Wnt antagonist genes (

Indexed as

DNA Methylationbeta CateninFemaleHumansIntercellular Signaling Peptides and ProteinsMalePrognosisProto-Oncogene ProteinsSecreted Frizzled-Related ProteinsStomach NeoplasmsWnt ProteinsWnt Signaling Pathwaybeta CateninCTNNB1 protein, humanDKK2 protein, humanIntercellular Signaling Peptides and ProteinsProto-Oncogene ProteinsSecreted Frizzled-Related ProteinsSFRP4 protein, humanWnt ProteinsDNA methylationgastric cancerprognosisWnt antagonistsβ-catenin

Identifiers

PMID28152305
PMCPMC5303888
OpenAlexW2587145129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.