Evidence map›Paper›PMID 28152301›Full record

ArticleMolecules and cells2017

Potentiation of T Cell Stimulatory Activity by Chemical Fixation of a Weak Peptide-MHC Complex.

Inkyu Hwang, Kwangmi Kim, Sojin Choi, Maria Lomunova

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Photochemical Treatment ofMediators of inflammation · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Inkyu HwangDepartment of Chemistry and Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
Kwangmi KimDepartment of Chemistry and Chemical Biology, The Scripps Research Institute, La Jolla, California, USA.
Sojin ChoiCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Maria LomunovaCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Chungnam National University · KRDankook University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The stability of peptide-MHC complex (pMHC) is an important factor to shape the fate of peptide-specific T cell immune response, but how it influences on T cell activation process is poorly understood. To better understand that, we investigated various T cell activation events driven by L

Indexed as

ActinsAnimalsCalciumHumansLymphocyte ActivationMajor Histocompatibility ComplexMiceMice, TransgenicPeptidesProtein BindingT-LymphocytesActinsCalciumPeptideschemical fixationparaformaldehydepeptide-MHC complexT cell activationT cell receptor

Identifiers

PMID28152301
PMCPMC5303886
OpenAlexW2591803006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.