Evidence map›Paper›PMID 28152256›Full record

ArticleJournal of magnetic resonance imaging : JMRI2017

Accelerated dual-venc 4D flow MRI for neurovascular applications.

Susanne Schnell, Sameer A Ansari, Can Wu, Julio Garcia, Ian G Murphy, Ozair A Rahman, Amir A Rahsepar, Maria Aristova, Jeremy D Collins, James C Carr and 1 more

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.

  1. 4D flow MRI for non-invasive measurement of blood flow in the brain: A systematic review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Pooled it
  2. Review
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  6. Fully self-gated dual-venc five-dimensional flow magnetic resonance imaging for simultaneous imaging of the cardiovascular and portal venous systems: A feasibility study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Article
  7. Mapping subarachnoid cerebrospinal fluid circulation in the human brain.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Comparison of free-running whole-heart five-dimensional and four-dimensional flow imaging to standard two-dimensional flow in patients with congenital heart disease.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
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  20. Verifying the Accuracy of Hemodynamic Analysis Using High Spatial Resolution 3D Phase-contrast MR Imaging on a 7T MR System: Comparison with a 3T System.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Susanne SchnellDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Sameer A AnsariDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Can WuDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Julio GarciaDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Ian G MurphyDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Ozair A RahmanDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Amir A RahseparDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Maria AristovaDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Jeremy D CollinsDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
James C CarrDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Michael MarklDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Functional Cardiovascular 4D MRI in Congenital Heart DiseaseR01HL115828 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MARKL, MICHAEL, RIGSBY, CYNTHIA K · 2012 to 2021
$5.2M
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS R01 HL115828
6 · The paper itself

Abstract

purposeTo improve velocity-to-noise ratio (VNR) and dynamic velocity range of 4D flow magnetic resonance imaging (MRI) by using dual-velocity encoding (dual-venc) with k-t generalized autocalibrating partially parallel acquisition (GRAPPA) acceleration. MATERIALS AND

methodsA dual-venc 4D flow MRI sequence with k-t GRAPPA acceleration was developed using a shared reference scan followed by three-directional low- and high-venc scans (repetition time / echo time / flip angle = 6.1 msec / 3.4 msec / 15°, temporal/spatial resolution = 43.0 msec/1.2 × 1.2 × 1.2 mm

resultsAll 4D flow MRI scans were acquired successfully with an acquisition time of 20 ± 4 minutes. The shared reference scan reduced the total acquisition time by 12.5% compared to two separate scans. Phantom experiments showed 51.4% reduced noise for dual-venc compared to high-venc and an excellent agreement of velocities (ρ = 0.8, P < 0.001). The volunteer data showed decreased noise in dual-venc data (54.6% lower) compared to high-venc, and improved image quality, as graded by two observers: fewer artifacts (P < 0.0001), improved vessel conspicuity (P < 0.0001), and reduced noise (P < 0.0001).

conclusionDual-venc 4D flow MRI exhibits the superior VNR of the low-venc acquisition and reliably incorporates low- and high-velocity fields simultaneously. In vitro and in vivo data demonstrate improved flow visualization, image quality, and image noise. LEVEL OF EVIDENCE: 2 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2017;46:102-114.

Indexed as

AdultBlood Flow VelocityBrainCardiac-Gated Imaging TechniquesCerebrovascular CirculationFemaleHumansImage EnhancementImaging, Three-DimensionalMagnetic Resonance AngiographyMaleMultimodal ImagingNeuroimagingNeurovascular CouplingPhantoms, ImagingReproducibility of Results4D flow MRIdual vencintracranial 4D flow MRIk-t GRAPPAPC-MRI

Identifiers

PMID28152256
PMCPMC5464980
OpenAlexW2583860532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.