ArticlePloS one2017
Physical activity and trajectories of frailty among older adults: Evidence from the English Longitudinal Study of Ageing.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05946109 (Tackling FRAILTY), which is not on this map. Cited by 94 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Tackling FRAILTY: ACTIVE-AGE@home: a Home-based Functional Exercise Program for Community Dwelling Frail Older Adults Provided by Professionals and Volunteers.
Who cites it
94 citing papers in PubMed, 2 syntheses or guidelines pooled it, 161 citations in OpenAlex.
- Aerobic physical activity, cardiorespiratory fitness, and non-communicable diseases risk in older adults: a systematic review.BMC geriatrics · 2026Pooled it
- A Systematic Review of Frailty Trajectories: Their Shape and Influencing Factors.The Gerontologist · 2021Pooled it
- Outdoor Exercise Facility-Based Integrative Mobile Health Intervention to Support Physical Activity, Mental Well-Being, and Exercise Self-Efficacy Among Older Adults With Prefrailty and Frailty in Hong Kong: Pilot Feasibility Randomized Controlled Trial Study.JMIR mHealth and uHealth · 2025Trial
- The effects of a moderate physical activity intervention on physical fitness and cognition in healthy elderly with low levels of physical activity: a randomized controlled trial.Alzheimer's research & therapy · 2023Trial
- Does Oral Health Status Predict Incident Frailty Over the 13-Year Follow-Up in Older Adults in England?Community dentistry and oral epidemiology · 2026Article
- Factors associated with sustained robustness in older adults: an 8-year multinational longitudinal study using SHARE data.BMC geriatrics · 2026Observational
- Article
- Long-Term Physical Activity Patterns and Risk of Future Frailty: A Systematic Review and Age-Stratified Meta-Analysis.Geriatrics (Basel, Switzerland) · 2026Review
- Effects of Isotemporal Substitution Analysis of Sedentary Behavior, Sleep, and Physical Activity on Physical Performance in Older Adults.Journal of prevention (2022) · 2026Article
- The joint association of sleep duration and physical activity with frailty among older adults: the first evidence from CHARLS.BMC geriatrics · 2026Article
- Longitudinal regimes of arts and cultural engagement and frailty among older adults in the United States: a g-formula approach.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Incidental Lifestyle Physical Activity and Its Relationships With Overall Frailty and Frailty Domains in Community-Dwelling Older Japanese.Geriatrics & gerontology international · 2026Article
- Evaluating the association of physical frailty with cognitive impairment: a clinical perspective in older adults of Bangladesh.BMC geriatrics · 2026Article
- Modifiable factors associated with frailty among indigenous older adults in southern Taiwan: a community-based cross-sectional study.Frontiers in public health · 2026Article
- Association of transitions in frailty with dementia risk: findings from two longitudinal cohort studies.Frontiers in medicine · 2026Article
- Relationships between physical activity dimensions and frailty incidence and progression in middle-aged and older adults: A 7-year cohort study.Journal of exercise science and fitness · 2026Article
- Baseline triglyceride-cholesterol-body weight index and risk of incident cardiovascular disease: evidence from the CHARLS and ELSA cohorts.Frontiers in nutrition · 2026Article
- Frailty and Physical Activity: A Compositional Isotemporal Substitution Analysis from the All of Us Research Program.Journal of frailty, sarcopenia and falls · 2025Article
- Article
- Association of physical activity levels with frailty index in elderly Chinese: evidence from the China health and retirement longitudinal study (CHARLS).BMC geriatrics · 2025Observational
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundFrail older adults are heavy users of health and social care. In order to reduce the costs associated with frailty in older age groups, safe and cost-effective strategies are required that will reduce the incidence and severity of frailty.
objectiveWe investigated whether self-reported intensity of physical activity (sedentary, mild, moderate or vigorous) performed at least once a week can significantly reduce trajectories of frailty in older adults who are classified as non-frail at baseline (Rockwood's Frailty Index [FI] ≤ 0.25).
methodsMulti-level growth curve modelling was used to assess trajectories of frailty in 8649 non-frail adults aged 50 and over and according to baseline self-reported intensity of physical activity. Frailty was measured in five-year age cohorts based on age at baseline (50-54; 55-59; 60-64; 65-69; 70-74; 75-79; 80+) on up to 6 occasions, providing an average of 10 years of follow-up. All models were adjusted for baseline sex, education, wealth, cohabitation, smoking, and alcohol consumption.
resultsCompared with the sedentary reference group, mild physical activity was insufficient to significantly slow the progression of frailty, moderate physical activity reduced the progression of frailty in some age groups (particularly ages 65 and above) and vigorous activity significantly reduced the trajectory of frailty progression in all older adults.
conclusionHealthy non-frail older adults require higher intensities of physical activity for continued improvement in frailty trajectories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.