Evidence map›Paper›PMID 28152044›Full record

ArticlePloS one2017

Microbiome sharing between children, livestock and household surfaces in western Kenya.

Emily Mosites, Matt Sammons, Elkanah Otiang, Alexander Eng, Cecilia Noecker, Ohad Manor, Sarah Hilton, Samuel M Thumbi, Clayton Onyango, Gemina Garland-Lewis and 10 more

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. The Enterics for Global Health (EFGH)Open forum infectious diseases · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Emily MositesUniversity of Washington, Department of Environmental and Occupational Health Sciences, Seattle, Washington, United States of America.
Matt SammonsWashington State University, Paul G. Allen School for Global Animal Health, Pullman, Washington, United States of America.
Elkanah OtiangKenya Medical Research Institute, Centre for Global Health Research, Kisumu, Kenya.
Alexander EngUniversity of Washington, Department of Genome Sciences, Seattle, Washington, United States of America.
Cecilia NoeckerUniversity of Washington, Department of Genome Sciences, Seattle, Washington, United States of America.
Ohad ManorUniversity of Washington, Department of Genome Sciences, Seattle, Washington, United States of America.
Sarah HiltonUniversity of Washington, Department of Genome Sciences, Seattle, Washington, United States of America.
Samuel M ThumbiWashington State University, Paul G. Allen School for Global Animal Health, Pullman, Washington, United States of America.
Clayton OnyangoKenya Medical Research Institute, Centre for Global Health Research, Kisumu, Kenya.
Gemina Garland-LewisUniversity of Washington, Department of Environmental and Occupational Health Sciences, Seattle, Washington, United States of America.
Douglas R CallWashington State University, Paul G. Allen School for Global Animal Health, Pullman, Washington, United States of America.
M Kariuki NjengaWashington State University, Paul G. Allen School for Global Animal Health, Pullman, Washington, United States of America.
Judith N WasserheitUniversity of Washington, Department of Global Health, Seattle, Washington, United States of America.
Jennifer A ZambriskiWashington State University, Paul G. Allen School for Global Animal Health, Pullman, Washington, United States of America.
Judd L WalsonUniversity of Washington, Department of Global Health, Seattle, Washington, United States of America.
Guy H PalmerWashington State University, Paul G. Allen School for Global Animal Health, Pullman, Washington, United States of America.
Joel MontgomeryCenters for Disease Control and Prevention, Division of Global Health Protection, Center for Global Health, Atlanta, Georgia, United States of America.
Elhanan BorensteinUniversity of Washington, Department of Genome Sciences, Seattle, Washington, United States of America.
Richard OmoreKenya Medical Research Institute, Centre for Global Health Research, Kisumu, Kenya.
Peter M RabinowitzUniversity of Washington, Department of Environmental and Occupational Health Sciences, Seattle, Washington, United States of America.

Funding

Infectious Diseases and Microbial Immunology Training ProgramT32AI007025 · NIAID · WASHINGTON STATE UNIVERSITY · PI Thomas H KAWULA, M KARIUKI NJENGA · 1985 to 2026
$7.4M
NIAID NIH HHS T32 AI007025
6 · The paper itself

Abstract

The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples from children and cattle, cloacal swabs from chickens, and swabs of household surfaces. Among the 156 households studied, children within the same household significantly shared their gut microbiome with each other, although we did not find significant sharing of gut microbiome across host species or household surfaces. Higher gut microbiome diversity among children was associated with lower wealth status and involvement in livestock feeding chores. Although more research is necessary to identify further drivers of microbiota development, these results suggest that the household should be considered as a unit. Livestock activities, health and microbiome perturbations among an individual child may have implications for other children in the household.

Indexed as

Gastrointestinal MicrobiomeAnimalsBiodiversityCattleChickensChild, PreschoolFamily CharacteristicsFecesFemaleHumansKenyaLivestockMalePoultryRNA, Ribosomal, 16SRural PopulationRNA, Ribosomal, 16S

Identifiers

PMID28152044
PMCPMC5289499

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.