Evidence map›Paper›PMID 28151851›Full record

Observational studyMedicine2017

True rise in anaphylaxis incidence: Epidemiologic study based on a national health insurance database.

Min-Suk Yang, Ju-Young Kim, Byung-Keun Kim, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Hye-Ryun Kang

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Global Burden of Drug-Induced Anaphylaxis Associated With 33 Classes of Antibiotics (1968-2024): A Pharmacovigilance Analysis.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
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  11. Recent update on the management of anaphylaxis.Clinical and experimental emergency medicine · 2021
    Article
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  20. HumanAsia Pacific allergy · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min-Suk YangDepartment of Internal medicine, SMG-SNU Boramae Medical Center Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul Department of Internal Medicine, Gyeongsang National University Hospital, Jinju Department of Internal medicine, Seoul National University Bundang Hospital, Seongnam Department of Internal medicine, Seoul National University College of Medicine Drug Safety Monitoring Center, Seoul National University Hospital, Seoul, Korea.
Ju-Young Kim
Byung-Keun Kim
Heung-Woo Park
Sang-Heon Cho
Kyung-Up Min
Hye-Ryun Kang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence trend of anaphylaxis in Asia is not well investigated. The aim of this study is to estimate the entire population-based incidence of anaphylaxis in Korea using a nationwide administrative database.Data over a 7-year period (2008-2014) was obtained from the Korean National Health Insurance (NHI) claims database which covers 97.9% of the entire Korean population. Using diagnosis codes from the International Classification of Diseases-10 for anaphylaxis (T78.0, T78.2, T80.5, and T88.6), we identified the annual number of patients who had visited any hospital with a primary diagnosis of anaphylaxis. Incidence rates were calculated using the population distribution data of all NHI beneficiaries.The incidence of anaphylaxis in Korea was 32.19 episodes per 100,000 person-years in 2014, which nearly doubled from 2008 (16.02 episodes per 100,000 person-years). The incidence of anaphylaxis increased continuously throughout these years regardless of gender and age groups (P for trend < 0.001). Female was significantly less predisposed than male (adjusted odds ratio [OR], 0.69; 95% confident interval [CI], 0.66-0.72; P < 0.001). The incidence was the lowest in 0 to 19 age group and the highest in 40 to 69 age group (adjusted OR, 2.41; 95% CI, 2.29-2.54; P < 0.001).In conclusion, we report the increasing time trend of anaphylaxis incidence rates using nationwide claims database for the first time in Asia.

Indexed as

AdolescentAdultAgedAge DistributionAnaphylaxisChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMaleMiddle AgedNational Health ProgramsOdds Ratio

Identifiers

PMID28151851
PMCPMC5293414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.