ArticlePain2017
Predictors of the transition from acute to persistent musculoskeletal pain in children and adolescents: a prospective study.
Article in Pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- Musculoskeletal pain in adolescents: a systematic review of predictive and associated factors.BMC pediatrics · 2026Pooled it
- Poor prognosis of child and adolescent musculoskeletal pain: a systematic literature review.BMJ open · 2019Pooled it
- Trial
- Somatosensory Function and Pain: Associations Over 12 Months Postinjury in Youth With Acute Musculoskeletal Pain.The Clinical journal of pain · 2026Article
- Persistent musculoskeletal pain and its association with future mental distress in adolescents: The Fit Futures study.BMC public health · 2025Article
- Multimodal hypersensitivity and somatic symptoms predict adolescent postmenarchal widespread pain.Pain · 2025Article
- Estimating the longitudinal association between pain characteristics and clinical outcomes in young people with mental ill-health.Psychological medicine · 2025Article
- Prognosis and bio-psycho-social prognostic factors in children and adolescents with musculoskeletal pain consulting general practice.European journal of pediatrics · 2025Observational
- Developing a Core Outcome Set for Pediatric and Adult Acute and Chronic Pain Extended Reality Trials: Delphi Consensus-Building Process.Journal of medical Internet research · 2025Article
- Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map.JMIR pediatrics and parenting · 2025Review
- [Advances of low-intensity pulsed ultrasound for treatment of musculoskeletal disorders in the past decade].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Review
- Early signs of long-term pain: prospective network profiles from late adolescence and lifelong follow-up.Npj mental health research · 2025Article
- Biopsychosocial risk factors for pain in early phases of pediatric cancer treatment.Frontiers in psychology · 2025Article
- Article
- Observational
- Mapping the Global Landscape of Temporomandibular Disorders Research in Children and Adolescents From 2000 to 2024: A Bibliometric Analysis.Pain research & management · 2025Review
- Daily and Weekly Associations Among Pain Intensity, Self-Reported Activity Limitations, and Objectively Assessed Physical Activity in Youth With Acute Musculoskeletal Pain.The journal of pain · 2024Article
- Pain and depressive symptoms among adolescents: prevalence and associations with achievement pressure and coping in the Norwegian Ungdata study.BMC public health · 2024Article
- Pain Catastrophizing Moderates the Relationship Between Pain Sensitivity and Clinical Pain in Adolescents With Functional Abdominal Pain.The journal of pain · 2024Article
- Biobehavioral Predictors of Pain Intensity, Pain Interference, and Chronic Pain Episodes: A Prospective Cohort Study of African-American Adults.The journal of pain · 2024Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Strategies directed at the prevention of disabling pain have been suggested as a public health priority, making early identification of youth at risk for poor outcomes critical. At present, limited information is available to predict which youth presenting with acute pain are at risk for persistence. The aims of this prospective longitudinal study were to identify biopsychosocial factors in the acute period that predict the transition to persistent pain in youth with new-onset musculoskeletal (MSK) pain complaints. Participants were 88 children and adolescents (age 10-17 years) presenting to the emergency department (n = 47) or orthopedic clinic (n = 41) for evaluation of a new MSK pain complaint (<1 month duration). Youth presented for 2 study visits (T1 ≤1 month post pain onset; T2 = 4-month follow-up) during which they completed questionnaires (assessing pain characteristics, psychological factors, sleep quality) and participated in a laboratory task assessing conditioned pain modulation. Regression analyses tested T1 predictors of longitudinal pain outcomes (pain persistence, pain-related disability, quality of life [QOL]). Results revealed approximately 35% of youth had persistent pain at 4-month follow-up, with persistent pain predicted by poorer conditioned pain modulation and female sex. Higher depressive symptoms at T1 were associated with higher pain-related disability and poorer QOL at T2. Findings highlight the roles of depressive symptoms and pain modulation in longitudinally predicting pain persistence in treatment-seeking youth with acute MSK pain and suggest potential mechanisms in the transition from acute to chronic MSK pain in children and adolescents.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.