ReviewChemical reviews2017
Ionic-Liquid-Mediated Extraction and Separation Processes for Bioactive Compounds: Past, Present, and Future Trends.
Review in Chemical reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
149 citing papers in PubMed.
- Thermophysical Properties of [EMIM][SCN] in Hydroxy-Based Solvents: Combined Experimental and Theoretical Analysis.ACS omega · 2026Article
- Tailored Diluent for Nanostructure and Viscosity Control in an Ionic Liquid.The journal of physical chemistry. B · 2026Article
- Hydrophobic deep eutectic solvents as sustainable media for ultrasound-assisted extraction of triterpenoids: a mechanistic and experimental study onRSC advances · 2026Article
- Dicationic ionic liquids as green functional materials.RSC advances · 2026Review
- Ionic Liquid-Assisted Sequential Ultrasound-Microwave Extraction of Monoterpene Glycosides fromMolecules (Basel, Switzerland) · 2026Article
- A high-yield, SPE-free DNA extraction method using a pyridinium-based ionic liquid compatible with downstream PCR analysis.Analytical and bioanalytical chemistry · 2026Article
- Molecular Extraction and Release of an Ionic Liquid Microdroplet With Dynamic Tunability Under Optical Trapping.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026Article
- Cation Functionalization Alters Cohesion, Not Interaction Type, in Ionic Liquids: Evidence from Infinite Dilution Activity Coefficients.The journal of physical chemistry. B · 2026Article
- Oppositely-charged coordination cages form a type I porous ionic liquid with two pore sizes.Materials horizons · 2026Article
- Preparation, Interaction Mechanism and Application of Functional Ionic Liquid-Mediated Protein Imprinting Technique.Polymers · 2026Review
- Superbase ionic liquid mediated solubilization of curcumin for improved bioavailability and anticancer efficacy.Scientific reports · 2026Article
- Deep eutectic solvents as recyclable media for metal removal from crude oil.RSC advances · 2026Article
- Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Elderberry and Linden Flowers Ethanol-Water Extracts: Extraction Type Effect, Analysis and Biological Activity Determination.Molecules (Basel, Switzerland) · 2026Article
- Integrating green chemistry with biomedical innovation: the role of biocompatible ionic liquids and ionic liquid nanoparticles in therapeutic applications.RSC advances · 2026Review
- Polyhedral Oligomeric Silsesquioxane-Based Ionic Liquids: Syntheses, Properties, and Applications.Chemical reviews · 2026Review
- Optimization of β-Carotene Extraction from Tucumã Fruit (ACS omega · 2025Article
- Advances in Microalgal Biomass Harvesting: Sustainable Approaches for Biofuel and Biorefinery Applications.Applied biochemistry and biotechnology · 2025Review
- l-Proline·HRSC advances · 2025Article
- Green astaxanthin extraction using microwave and ultrasound pretreatments.NPJ science of food · 2025Article
89 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Ionic liquids (ILs) have been proposed as promising media for the extraction and separation of bioactive compounds from the most diverse origins. This critical review offers a compilation on the main results achieved by the use of ionic-liquid-based processes in the extraction and separation/purification of a large range of bioactive compounds (including small organic extractable compounds from biomass, lipids, and other hydrophobic compounds, proteins, amino acids, nucleic acids, and pharmaceuticals). ILs have been studied as solvents, cosolvents, cosurfactants, electrolytes, and adjuvants, as well as used in the creation of IL-supported materials for separation purposes. The IL-based processes hitherto reported, such as IL-based solid-liquid extractions, IL-based liquid-liquid extractions, IL-modified materials, and IL-based crystallization approaches, are here reviewed and compared in terms of extraction and separation performance. The key accomplishments and future challenges to the field are discussed, with particular emphasis on the major lacunas found within the IL community dedicated to separation processes and by suggesting some steps to overcome the current limitations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.