ArticleJournal of child psychology and psychiatry, and allied disciplines2017
Developmental change in the association between adolescent depressive symptoms and the home environment: results from a longitudinal, genetically informative investigation.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Parenting practices in childhood and depression, anxiety, and internalizing symptoms in adolescence: a systematic review.Social psychiatry and psychiatric epidemiology · 2021Pooled it
- Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Clinical factors associated with genetic diagnosis in suspected neurogenetic disorders in a tertiary care clinic.Genetics in medicine : official journal of the American College of Medical Genetics · 2025Article
- Evaluating Machine Learning Stability in Predicting Depression and Anxiety Amidst Subjective Response Errors.Healthcare (Basel, Switzerland) · 2024Article
- Socioeconomic status and risk for child psychopathology: exploring gene-environment interaction in the presence of gene-environment correlation using extended families in the Norwegian Mother, Father and Child Birth Cohort Study.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
- Parental criticism and adolescent internalising symptoms: using a Children-of-Twins design with power calculations to account for genetic influence.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- Article
- AVPR1A main effect and OXTR-by-environment interplay in individual differences in depression level.Heliyon · 2020Article
- The relationship between household chaos and child, parent, and family outcomes: a systematic scoping review.BMC public health · 2020Article
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Authors and funding
3 authors.
Funding
Abstract
backgroundDepression is already highly prevalent by late adolescence, indicating that research into its developmental emergence should consider earlier risk factors and environmental contexts. The home environment is a key context for children and adolescents throughout development. However, the nature of relationships that exist between aspects of the home environment and the development of depressive symptoms cannot be assumed. Genetically informative studies have been used to provide insights about the aetiology of such relationships, often finding them to be partly confounded by the influence of children's genes. Here, we investigate developmental change in the aetiology of the association between aspects of the home environment and depressive symptoms at the onset of adolescence.
methodsWe used longitudinal child- and parent-report data from >5,000 twin pairs enrolled in the UK-representative Twins Early Development Study. Multivariate, genetically sensitive structural equation models were used to decompose latent variance and covariance in depressive symptoms (measured at 12 and 16 years) and aspects of the home environment (at 9 and 14 years) into genetic and environmental influences.
resultsGoing from childhood to adolescence, genetic influences accounted for an increasing proportion of the association [30% (16-42) of r = .44 in childhood; 40% (25-61) of r = .43 in adolescence], at the expense of shared environmental influences, which decreased from 70% (58-83) to 48% (29-62). Unique environmental influences accounted for a significant proportion of the association in adolescence only [12% (06-18)]. Developmental changes could largely be attributed to subtle shifts in the relative importance of stable aetiological factors, rather than the emergence of influences unique to adolescence.
conclusionsThese findings emphasise the importance of developmental and aetiological context in interpreting associations between aspects of the home environment and child emotional outcomes.
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