ReviewDisease models & mechanisms2017
Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models.
Review in Disease models & mechanisms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 151 citations in OpenAlex.
- Managing dangerous liaisons: lessons fromJournal of bacteriology · 2026Review
- Current concepts of Helicobacter pylori infection.European journal of medical research · 2025Review
- Pathogenicity and virulence ofVirulence · 2025Review
- Autophagy-driven modulation of stem cell dynamics inVirulence · 2025Article
- Gastric organoids: A promising model for studying "inflammation-cancer" transition in atrophic gastritis.World journal of clinical oncology · 2025Review
- Review
- TargetingNutrients · 2025Review
- Standardized aqueous extract ofFrontiers in pharmacology · 2025Article
- A critical review onFrontiers in cellular and infection microbiology · 2025Review
- Prevalence and resistance ofWorld journal of gastrointestinal endoscopy · 2024Article
- Chemical burn wounds as a risk factor for gastric cancer: in-silico analyses-experimental research.Annals of medicine and surgery (2012) · 2024Article
- Exploring the Link betweenAntibiotics (Basel, Switzerland) · 2024Review
- Chebulinic acid isolated from aqueous extracts ofFrontiers in microbiology · 2024Article
- Review
- Global trends of cancer: The role of diet, lifestyle, and environmental factors.Cancer innovation · 2023Review
- Article
- Management of dyspepsia and Helicobacter pylori infection: the 2022 Indonesian Consensus Report.Gut pathogens · 2023Review
- Pathologic characteristics of infectious diseases in macaque monkeys used in biomedical and toxicologic studies.Journal of toxicologic pathology · 2023Review
- Article
- A 3D co-culture intestinal organoid system for exploring glucose metabolism.Current research in food science · 2023Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric colonization with Helicobacter pylori induces diverse human pathological conditions, including superficial gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric adenocarcinoma and its precursors. The treatment of these conditions often relies on the eradication of H. pylori, an intervention that is increasingly difficult to achieve and that does not prevent disease progression in some contexts. There is, therefore, a pressing need to develop new experimental models of H. pylori-associated gastric pathology to support novel drug development in this field. Here, we review the current status of in vivo and ex vivo models of gastric H. pylori colonization, and of Helicobacter-induced gastric pathology, focusing on models of gastric pathology induced by H. pylori, Helicobacter felis and Helicobacter suis in rodents and large animals. We also discuss the more recent development of gastric organoid cultures from murine and human gastric tissue, as well as from human pluripotent stem cells, and the outcomes of H. pylori infection in these systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.