Evidence map›Paper›PMID 28151394›Full record

ArticleBlood transfusion = Trasfusione del sangue2017

A fast-track anaemia clinic in the Emergency Department: cost-analysis of intravenous iron administration for treating iron-deficiency anaemia.

Manuel Quintana-Díaz, Raúl Muñoz-Romo, Susana Gómez-Ramírez, José Pavía, Alberto M Borobia, José A García-Erce, Manuel Muñoz

Open access · greenAbstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Fast Track Anaemia Clinic (FTAC) and Intravenous Iron Administration: Its Relevance and Application Today in India.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2018
    Article
  12. Article
  13. Current misconceptions in diagnosis and management of iron deficiency.Blood transfusion = Trasfusione del sangue · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Manuel Quintana-DíazIntensive Care Unit, University Hospital La Paz, Madrid, Spain.
Raúl Muñoz-RomoClinical Pharmacology, School of Medicine, Autonomous University of Madrid, Madrid, Spain.
Susana Gómez-RamírezInternal Medicine, University Hospital Virgen de la Victoria, Málaga, Spain.
José PavíaPharmacology, School of Medicine, University of Málaga, Málaga, Spain.
Alberto M BorobiaResearch Institute, University Hospital La Paz (IdiPAZ), Madrid, Spain.
José A García-ErceResearch Institute, University Hospital La Paz (IdiPAZ), Madrid, Spain.
Manuel MuñozTransfusion Medicine, School of Medicine, University of Málaga, Málaga, Spain.
Hospital La Paz Institute for Health Research · ESUniversidad de Málaga · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA fast-track anaemia clinic (FTAC) for the management of moderate-to-severe iron-deficiency anaemia (IDA) was established in our Emergency Department in 2010. In this FTAC, the replacement of packed red cell transfusion by ferric carboxymaltose administration was proven to be safe and effective. The aim of this study was a cost-analysis of IDA management in the FTAC, comparing this management with the previous standard care pathway consisting of packed red cell transfusion, if needed, and referral to outpatient specialised care. MATERIALS AND

methodsA cost study was performed for patients with IDA who were at risk of requiring transfusion (haemoglobin <9 g/dL) but did not require hospitalisation. Total IDA treatment costs in the FTAC were compared to those theoretically incurred if these patients had been managed using the standard care pathway. In addition, a sensitivity analysis considering variations of up to ±30% in ferric carboxymaltose and packed red cell acquisition costs was performed (49 possible scenarios).

resultsBetween 2012 and 2015, 238 IDA patients were treated in the FTAC. The average treatment cost was € 594±337/patient in the FTAC group and € 672±301/patient in the standard care pathway group, with a saving of € 78±28/patient (95% CI, 22-133; p<0.001). The sensitivity analysis showed that IDA treatment costs in the FTAC (€ 480-722/patient), compared with those of the standard care pathway (€ 550-794/patient), resulted in significant cost-savings for all studied scenarios (€ 51-104/patient; p<0.005). DISCUSSION: The administration of ferric carboxymaltose for IDA management in a FTAC may be cost-saving compared with the standard care pathway.

Indexed as

Administration, IntravenousAdultAgedAged, 80 and overAnemia, Iron-DeficiencyCosts and Cost AnalysisEmergency Service, HospitalFemaleFerric CompoundsHumansIronMaleMaltoseMiddle Agedferric carboxymaltoseFerric CompoundsIronMaltose

Identifiers

PMID28151394
PMCPMC5589706
OpenAlexW2586382652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.