ArticleMagnetic resonance in medicine2017
Spectral characteristics of semisolid protons in human brain white matter at 7 T.
Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Parallel transmit pulse design for saturation homogeneity (PUSH) for magnetization transfer imaging at 7T.Magnetic resonance in medicine · 2022Article
- BNeuroImage · 2020Article
- White matter intercompartmental water exchange rates determined from detailed modeling of the myelin sheath.Magnetic resonance in medicine · 2019Article
- Rapid and quantitative chemical exchange saturation transfer (CEST) imaging with magnetic resonance fingerprinting (MRF).Magnetic resonance in medicine · 2018Article
- Separating fast and slow exchange transfer and magnetization transfer using off-resonance variable-delay multiple-pulse (VDMP) MRI.Magnetic resonance in medicine · 2018Article
- CEST, ASL, and magnetization transfer contrast: How similar pulse sequences detect different phenomena.Magnetic resonance in medicine · 2018Review
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Authors and funding
3 authors.
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Abstract
purposeTo inform the quantification of MRI magnetization transfer contrast at high field by measuring the spectral characteristics of
methodsSaturation-recovery type experiments were performed using brief, frequency-specific RF pulses that saturate semisolid proton magnetization. Analysis of the subsequent recovery of water proton magnetization with a two-pool model of exchange allowed the study of spectral characteristics of semisolid protons.
resultsWe show that in white matter, the semisolid proton spectrum can be approximated with a symmetric, super-Lorentzian line at -2.58 ± 0.05 ppm from the water resonance and an average transverse relaxation time constant (T
conclusionsThese results are consistent with studies at lower field that have indicated a major contribution from methylene protons to magnetization transfer contrast, and will facilitate the design and quantification of magnetization transfer studies at 7 T. Magn Reson Med 78:1950-1958, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
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