Evidence map›Paper›PMID 28150215›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2017

Pulmonary Delivery of Magnetically Targeted Nano-in-Microparticles.

Amber A McBride, Dominique N Price, Pavan Muttil

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amber A McBrideSandia National Laboratories, Albuquerque, NM, USA.
Dominique N PriceDepartment of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Suite 208, 2705 Frontier Ave NE, Albuquerque, NM, 87106, USA.
Pavan MuttilDepartment of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Suite 208, 2705 Frontier Ave NE, Albuquerque, NM, 87106, USA. pmuttil@salud.unm.edu.
University of New Mexico · USSandia National Laboratories · US

Funding

Biology of Infectious Diseases &InflammationT32AI007538 · NIAID · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Michelle A Ozbun · 1998 to 2026
$5.2M
NIAID NIH HHS T32 AI007538
6 · The paper itself

Abstract

This chapter details the intratracheal delivery of dry powder microparticles termed nano-in-microparticles (NIMs) for the purpose of in vivo targeted pulmonary drug delivery. The dry powder NIMs technology improves on previous inhaled chemotherapy platforms designed as liquid formulations. Dry powder microparticles were created through the process of spray drying; a protocol detailing the formulation of NIMs dry powder is included as a separate chapter in this book. Dry powder NIMs containing fluorescent nanoparticles and magnetically-responsive superparamagnetic iron oxide nanoparticles are intratracheally delivered (insufflated) in the presence of a magnetic field and targeted to the left lung of mice. The targeting efficiency of dry powder NIMs is compared to the targeting efficiency of liquid NIMs to demonstrate the superiority of dry power targeting platforms. Targeting is assessed using fluorescence associated with NIMs detected in the mouse trachea, left lung, and right lung by an in vivo imaging system.

Indexed as

Drug CarriersDrug Delivery SystemsLungMagnetite NanoparticlesAdministration, InhalationAnimalsIntubation, IntratrachealMiceDrug CarriersMagnetite NanoparticlesDry powderInsufflationIntratracheal deliveryIron oxide nanoparticlesNano-in-microparticlesPulmonary deliverySuperparamagnetismTargeted drug delivery

Identifiers

PMID28150215
PMCPMC7519880
OpenAlexW2586042404

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.