ArticleJournal of materials science. Materials in medicine2017
Green synthesis of rifampicin-loaded copper nanoparticles with enhanced antimicrobial activity.
Article in Journal of materials science. Materials in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 53 citations in OpenAlex.
- Star Polymers as a Reducing Agent of Silver Salt and a Carrier for Silver Nanoparticles.Materials (Basel, Switzerland) · 2025Article
- NLC-Based Rifampicin Delivery System: Development and Characterization for Improved Drug Performance AgainstPharmaceutics · 2025Article
- Nanogels conjugated with cell-penetrating peptide as drug delivery vehicle for treating urinary tract infections.Nanomedicine : nanotechnology, biology, and medicine · 2025Article
- A Review on Bioflocculant-Synthesized Copper Nanoparticles: Characterization and Application in Wastewater Treatment.Bioengineering (Basel, Switzerland) · 2024Review
- Advancements in Green Nanoparticle Technology: Focusing on the Treatment of Clinical Phytopathogens.Biomolecules · 2024Review
- Nanocarriers in Tuberculosis Treatment: Challenges and Delivery Strategies.Pharmaceuticals (Basel, Switzerland) · 2023Review
- ZnO size and shape effect on antibacterial activity and cytotoxicity profile.Scientific reports · 2022Article
- Metal-based nano-delivery platform for treating bone disease and regeneration.Frontiers in chemistry · 2022Review
- Nanomaterials to address the genesis of antibiotic resistance inFrontiers in cellular and infection microbiology · 2022Review
- Design of a Controlled-Release Delivery Composite of Antibacterial Agent Gatifloxacin by Spherical Silica Nanocarrier.Frontiers in chemistry · 2021Article
- Fabrication of Gelatin-ZnO Nanofibers for Antibacterial Applications.Materials (Basel, Switzerland) · 2020Article
- The Demand for New Antibiotics: Antimicrobial Peptides, Nanoparticles, and Combinatorial Therapies as Future Strategies in Antibacterial Agent Design.Frontiers in microbiology · 2020Review
- Nano-mediated delivery of double-stranded RNA for gene therapy of glioblastoma multiforme.PloS one · 2019Article
- Gel with silver and ultrasmall iron oxide nanoparticles produced with Amanita muscaria extract: physicochemical characterization, microstructure analysis and anticancer properties.Scientific reports · 2018Article
- Novel synthesis and characterization of pristine Cu nanoparticles for the non-enzymatic glucose biosensor.Journal of materials science. Materials in medicine · 2017Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The antimicrobial properties of copper and rifampicin-loaded copper nanoparticles were investigated using four strains: Staphylococcus aureus, Escherichia coli, Bacillus pumilis and Pseudomonas fluorescens. Spherical-shaped copper nanoparticles were synthesized via green reduction method from the peppermint extract. It was found that adsorption of rifampicin on the copper nanosurface enhances its biological activity and prevents the development of resistance. The interactions between rifampicin-copper nanoparticles and bacteria cells were monitored using atomic force microscopy (AFM) and confocal laser scanning microscopy (CLSM). It was proven that loaded with rifampicin copper nanoparticles were able to damage the S. aureus cell membrane and facilitate the bacteria biofilm matrix disintegration. Moreover, the DNA decomposition of S. aureus treated with copper and rifampicin-copper nanoparticles was confirmed by agarose gel electrophoresis. The results obtained indicate that adsorption of rifampicin on the copper nanoparticles surface might provide the reduction of antibiotic dosage and prevent its adverse side effects.
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