Evidence map›Paper›PMID 28149992›Full record

ArticleChemical communications (Cambridge, England)2017

A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging.

F Doria, M Nadai, M Zuffo, R Perrone, M Freccero, S N Richter

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 62 citations in OpenAlex.

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  12. Subcellular Duplex DNA and G-Quadruplex Interaction Profiling of a Hexagonal PtAngewandte Chemie (International ed. in English) · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

F DoriaDept. of Chemistry, University of Pavia, V.le Taramelli 10, 27100 Pavia, Italy. mauro.freccero@unipv.it.ORCID http://orcid.org/0000-0002-1308-1060
M NadaiDept. of Molecular Medicine, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.ORCID http://orcid.org/0000-0003-3831-4892
M ZuffoDept. of Chemistry, University of Pavia, V.le Taramelli 10, 27100 Pavia, Italy. mauro.freccero@unipv.it.
R PerroneDept. of Molecular Medicine, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.ORCID http://orcid.org/0000-0001-8894-4548
M FrecceroDept. of Chemistry, University of Pavia, V.le Taramelli 10, 27100 Pavia, Italy. mauro.freccero@unipv.it.ORCID http://orcid.org/0000-0002-7438-1526
S N RichterDept. of Molecular Medicine, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.
University of Padua · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggregation, red-NIR emission and light-up upon nucleic acid G-quadruplex binding have been investigated for a prototype core-extended naphthalene diimide, which is capable of fast cellular entry and nucleolar localization. Both high-level colocalization with an anti-G-quadruplex antibody and nucleolin displacement reveal that the compound targets and thus makes visible nuclear DNA G-quadruplexes.

Indexed as

G-QuadruplexesAntibodiesCell NucleusChromosomal Proteins, Non-HistoneFluorescent DyesHEK293 CellsHumansImidesMicroscopy, ConfocalNaphthalenesSpectrometry, FluorescenceAntibodiesChromosomal Proteins, Non-HistonefibrillarinFluorescent DyesImidesnaphthalenediimideNaphthalenes

Identifiers

PMID28149992
PMCPMC5471928
OpenAlexW2583080711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.