Evidence map›Paper›PMID 28149967›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2016

3D Deep Learning for Multi-modal Imaging-Guided Survival Time Prediction of Brain Tumor Patients.

Dong Nie, Han Zhang, Ehsan Adeli, Luyan Liu, Dinggang Shen

Open access · greenAbstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
86.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 286 citations in OpenAlex.

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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dong NieDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Han ZhangDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Ehsan AdeliDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Luyan LiuDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, USA.
University of North Carolina at Chapel Hill · US

Funding

Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
NIBIB NIH HHS R01 EB008374
6 · The paper itself

Abstract

High-grade glioma is the most aggressive and severe brain tumor that leads to death of almost 50% patients in 1-2 years. Thus, accurate prognosis for glioma patients would provide essential guidelines for their treatment planning. Conventional survival prediction generally utilizes clinical information and limited handcrafted features from magnetic resonance images (MRI), which is often time consuming, laborious and subjective. In this paper, we propose using deep learning frameworks to automatically extract features from multi-modal preoperative brain images (i.e., T1 MRI, fMRI and DTI) of high-grade glioma patients. Specifically, we adopt 3D convolutional neural networks (CNNs) and also propose a new network architecture for using multi-channel data and learning supervised features. Along with the pivotal clinical features, we finally train a support vector machine to predict if the patient has a long or short overall survival (OS) time. Experimental results demonstrate that our methods can achieve an accuracy as high as 89.9% We also find that the learned features from fMRI and DTI play more important roles in accurately predicting the OS time, which provides valuable insights into functional neuro-oncological applications.

Indexed as

AlgorithmsDeep LearningLife ExpectancyBrainBrain NeoplasmsGliomaHumansMagnetic Resonance ImagingMultimodal ImagingNeoplasm GradingNeural Networks, ComputerPrognosisReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID28149967
PMCPMC5278791
OpenAlexW2525157777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.