ArticlePreventive medicine reports2017
Associations of objectively measured moderate-to-vigorous-intensity physical activity and sedentary time with all-cause mortality in a population of adults at high risk of type 2 diabetes mellitus.
Article in Preventive medicine reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies.British journal of sports medicine · 2022Pooled it
- Joint associations of accelero-meter measured physical activity and sedentary time with all-cause mortality: a harmonised meta-analysis in more than 44 000 middle-aged and older individuals.British journal of sports medicine · 2020Pooled it
- Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis.BMJ (Clinical research ed.) · 2019Pooled it
- Effect of novel technology-enabled multidimensional physical activity feedback in primary care patients at risk of chronic disease - the MIPACT study: a randomised controlled trial.The international journal of behavioral nutrition and physical activity · 2020Trial
- Intensity of physical activity and cardiovascular and all-cause mortality in diabetic patients: A cohort study (NHANES 1999-2018).Medicine · 2026Article
- Accelerometer-Measured Sedentary Behavior and Risk of Future Cardiovascular Disease.Journal of the American College of Cardiology · 2025Article
- Accelerometer-derived physical activity and mortality in individuals with type 2 diabetes.Nature communications · 2024Article
- Timing of Moderate to Vigorous Physical Activity, Mortality, Cardiovascular Disease, and Microvascular Disease in Adults With Obesity.Diabetes care · 2024Article
- Review
- Association between domain-specific physical activity and diabetes in Korean adults.Scientific reports · 2021Article
- Factors Associated with the 4-Year Estimated Incidence of Type 2 Diabetes Mellitus by Sex in Korean Adults: Secondary Data Analysis.International journal of endocrinology · 2021Article
- Body Fat Is Related to Sedentary Behavior and Light Physical Activity but Not to Moderate-Vigorous Physical Activity in Type 2 Diabetes Mellitus.Diabetes & metabolism journal · 2020Article
- Physical activity in women with subclinical hypothyroidism.Journal of endocrinological investigation · 2019Article
- Moderate-to-Vigorous Physical Activity and All-Cause Mortality: Do Bouts Matter?Journal of the American Heart Association · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationships of physical activity and sedentary time with all-cause mortality in those at high risk of type 2 diabetes mellitus (T2DM) are unexplored. To address this gap in knowledge, we examined the associations of objectively measured moderate-to-vigorous-intensity physical activity (MVPA) and sedentary time with all-cause mortality in a population of adults at high risk of T2DM. In 2010-2011, 712 adults (Leicestershire, U.K.), identified as being at high risk of T2DM, consented to be followed up for mortality. MVPA and sedentary time were assessed by accelerometer; those with valid data (≥ 10 hours of wear-time/day with ≥ 4 days of data) were included. Cox proportional hazards regression models, adjusted for potential confounders, were used to investigate the independent associations of MVPA and sedentary time with all-cause mortality. 683 participants (250 females (36.6%)) were included and during a mean follow-up period of 5.7 years, 26 deaths were registered. Every 10% increase in MVPA time/day was associated with a 5% lower risk of all-cause mortality [Hazard Ratio (HR): 0.95 (95% Confidence Interval (95% CI): 0.91, 0.98); p = 0.004]; indicating that for the average adult in this cohort undertaking approximately 27.5 minutes of MVPA/day, this benefit would be associated with only 2.75 additional minutes of MVPA/day. Conversely, sedentary time showed no association with all-cause mortality [HR (every 10-minute increase in sedentary time/day): 0.99 (95% CI: 0.95, 1.03); p = 0.589]. These data support the importance of MVPA in adults at high risk of T2DM. The association between sedentary time and mortality in this population needs further investigation.
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