Evidence map›Paper›PMID 28149704›Full record

ArticleBiochemistry & physiology2016

Cancer Therapeutics Following Newton's Third Law.

Ali S Arbab, Meenu Jain, Bhagelu R Achyut

Abstract read
In one paragraph

Article in Biochemistry & physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ali S ArbabTumor Angiogenesis Lab, Cancer Center, Augusta University, Augusta 30907, GA, USA.
Meenu JainTumor Angiogenesis Lab, Cancer Center, Augusta University, Augusta 30907, GA, USA.
Bhagelu R AchyutTumor Angiogenesis Lab, Cancer Center, Augusta University, Augusta 30907, GA, USA.

Funding

Understanding Mechanisms of Resistance to Anti-angiogenic TreatmentsR01CA160216 · NCI · HENRY FORD HEALTH SYSTEM · PI ARBAB, ALI SYED · 2012 to 2016
$1.8M
In vivo detection of involvement of endogenous BM progenitor cells in gliomaR01CA172048 · NCI · HENRY FORD HEALTH SYSTEM · PI ARBAB, ALI SYED · 2012 to 2014
$894k
NCI NIH HHS R01 CA160216NCI NIH HHS R01 CA172048
6 · The paper itself

Abstract

Cancer is a wound that never heals. This is suggested by the data produced after several years of cancer research and therapeutic interventions done worldwide. There is a strong similarity between Newton's third law and therapeutic behavior of tumor. According to Newton's third law "for every action, there is an equal and opposite reaction". In cancer therapeutics, tumor exerts strong pro-tumor response against applied treatment and imposes therapeutic resistance, one of the major problems seen in preclinical and clinical studies. There is an urgent need to understand the tumor biology of therapy resistant tumors following the therapy. Here, we have discussed the problem and provided possible path for future studies to treat cancer.

Identifiers

PMID28149704
PMCPMC5279577

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.