ArticlePeerJ2017
Antibiotic resistance potential of the healthy preterm infant gut microbiome.
Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Pooled it
- The Microbiome of Infants Recruited to a Randomised Placebo-controlled Probiotic Trial (PiPS Trial).EBioMedicine · 2017Trial
- Trial
- Age- and diet-driven assembly of the gut antibiotic resistome in humans and food-producing animals.Gut microbes · 2026Review
- Broad-spectrum antibiotic treatment reshapes the gut microbiome, resistome, and colonization potential of opportunistic pathogens: a metagenomics study.Gut pathogens · 2026Article
- Early-life microbiome trajectories as biomarkers to predict health outcomes.Microbiome research reports · 2026Review
- The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Baseline azithromycin resistance in the gut microbiota of preterm born infants.Pediatric research · 2024Article
- Impact of long-term dietary habits on the human gut resistome in the Dutch population.Scientific reports · 2022Article
- Effect of a reduced fat and sugar maternal dietary intervention during lactation on the infant gut microbiome.Frontiers in microbiology · 2022Article
- Premature neonatal gut microbial community patterns supporting an epithelial TLR-mediated pathway for necrotizing enterocolitis.BMC microbiology · 2021Article
- Microbiota Supplementation withCell reports. Medicine · 2020Observational
- Dynamics of toxigenic Clostridium perfringens colonisation in a cohort of prematurely born neonatal infants.BMC pediatrics · 2020Article
- Abundance and diversity of resistomes differ between healthy human oral cavities and gut.Nature communications · 2020Article
- Perinatal risk factors for fecal antibiotic resistance gene patterns in pregnant women and their infants.PloS one · 2020Article
- Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome.Nature microbiology · 2019Article
- Early-life gut microbiome modulation reduces the abundance of antibiotic-resistant bacteria.Antimicrobial resistance and infection control · 2019Article
- Indexed variation graphs for efficient and accurate resistome profiling.Bioinformatics (Oxford, England) · 2018Article
- WHAM!: a web-based visualization suite for user-defined analysis of metagenomic shotgun sequencing data.BMC genomics · 2018Article
- The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.Microbiome · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew studies have investigated the gut microbiome of infants, fewer still preterm infants. In this study we sought to quantify and interrogate the resistome within a cohort of premature infants using shotgun metagenomic sequencing. We describe the gut microbiomes from preterm but healthy infants, characterising the taxonomic diversity identified and frequency of antibiotic resistance genes detected.
resultsDominant clinically important species identified within the microbiomes included
conclusionsWe found that the healthy preterm infant gut microbiomes in this study harboured a significant diversity of antibiotic resistance genes. This broad picture of resistances and the wider taxonomic diversity identified raises further caution to the use of antibiotics without consideration of the resident microbial communities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.